NLE1 (NM_018096) Human Tagged ORF Clone Lentiviral Particle

SKU RC204114L3V

Lenti ORF particles, NLE1 (Myc-DDK tagged) - Human notchless homolog 1 (Drosophila) (NLE1), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: NLE1
• Synonyms: NLE
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204114).
• ACCN: NM_018096
• ORF Size: 1455 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_018096.3
• RefSeq Size: 2627 bp
• RefSeq ORF: 1458 bp
• Locus ID: 54475
• UniProt ID: Q9NVX2
• Cytogenetics: 17q12
• Domains: WD40
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• MW: 53.3 kDa
• Summary: Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several members of the Wnt pathway, probably via its effects on Notch activity. Required during embryogenesis for inner mass cell survival (By similarity).[UniProtKB/Swiss-Prot Function]