coproporphyrinogen oxidase (CPOX) (NM_000097) Human Tagged ORF Clone Lentiviral Particle

SKU RC204033L3V

Lenti ORF particles, CPOX (Myc-DDK-tagged)-Human coproporphyrinogen oxidase (CPOX), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: coproporphyrinogen oxidase
• Synonyms: COX; CPO; CPX; HARPO; HCP
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204033).
• ACCN: NM_000097
• ORF Size: 1362 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_000097.5
• RefSeq Size: 2728 bp
• RefSeq ORF: 1365 bp
• Locus ID: 1371
• UniProt ID: P36551
• Cytogenetics: 3q11.2
• Domains: Coprogen_oxidas
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Porphyrin and chlorophyll metabolism
• MW: 50.6 kDa
• Summary: The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).[provided by RefSeq, Oct 2009]