SIPA1 (NM_153253) Human Tagged ORF Clone Lentiviral Particle

SKU RC203747L4V

Lenti ORF particles, SIPA1 (mGFP-tagged)-Human signal-induced proliferation-associated 1 (SIPA1), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: SIPA1
• Synonyms: SPA1
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203747).
• ACCN: NM_153253
• ORF Size: 3126 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_153253.28, NP_694985.28
• RefSeq Size: 3657 bp
• RefSeq ORF: 3129 bp
• Locus ID: 6494
• UniProt ID: Q96FS4
• Cytogenetics: 11q13.1
• Domains: PDZ, Rap_GAP
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS
• Protein Pathways: Leukocyte transendothelial migration
• MW: 112 kDa
• Summary: The product of this gene is a mitogen induced GTPase activating protein (GAP). It exhibits a specific GAP activity for Ras-related regulatory proteins Rap1 and Rap2, but not for Ran or other small GTPases. This protein may also hamper mitogen-induced cell cycle progression when abnormally or prematurely expressed. It is localized to the perinuclear region. Two alternatively spliced variants encoding the same isoform have been characterized to date. [provided by RefSeq, Jul 2008]