BRMS1 (NM_015399) Human Tagged ORF Clone Lentiviral Particle
SKU
RC203428L3V
Lenti ORF particles, BRMS1 (Myc-DDK tagged) - Human breast cancer metastasis suppressor 1 (BRMS1), transcript variant 1, 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | BRMS1 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC203428).
|
ACCN | NM_015399 |
ORF Size | 738 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_015399.3 |
RefSeq Size | 1455 bp |
RefSeq ORF | 741 bp |
Locus ID | 25855 |
UniProt ID | Q9HCU9 |
Cytogenetics | 11q13.2 |
Protein Families | Druggable Genome |
MW | 28.5 kDa |
Summary | This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
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