ASCC2 (NM_032204) Human Tagged ORF Clone Lentiviral Particle

SKU RC203391L3V

Lenti ORF particles, ASCC2 (Myc-DDK tagged) - Human activating signal cointegrator 1 complex subunit 2 (ASCC2), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: ASCC2
• Synonyms: ASC1p100; p100
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203391).
• ACCN: NM_032204
• ORF Size: 2271 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_032204.3
• RefSeq Size: 2840 bp
• RefSeq ORF: 2274 bp
• Locus ID: 84164
• UniProt ID: Q9H1I8
• Cytogenetics: 22q12.2
• Domains: CUE
• Protein Families: Druggable Genome, Transcription Factors
• MW: 86.4 kDa
• Summary: Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains (PubMed:29144457). Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation (PubMed:12077347).[UniProtKB/Swiss-Prot Function]