DEM1 (EXO5) (NM_022774) Human Tagged ORF Clone Lentiviral Particle

SKU RC203370L3V

Lenti ORF particles, EXO5 (Myc-DDK tagged) - Human defects in morphology 1 homolog (S. cerevisiae) (DEM1), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: DEM1
• Synonyms: C1orf176; DEM1; Exo V; hExo5
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203370).
• ACCN: NM_022774
• ORF Size: 1119 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_022774.1
• RefSeq Size: 2217 bp
• RefSeq ORF: 1122 bp
• Locus ID: 64789
• UniProt ID: Q9H790
• Cytogenetics: 1p34.2
• MW: 41.9 kDa
• Summary: The protein encoded by this gene is a single-stranded DNA (ssDNA)-specific exonuclease that can slide along the DNA before cutting it. However, human replication protein A binds ssDNA and restricts sliding of the encoded protein, providing a 5'-directionality to the enzyme. This protein localizes to nuclear repair loci after DNA damage. [provided by RefSeq, Nov 2016]