Kallikrein 2 (KLK2) (NM_005551) Human Tagged ORF Clone Lentiviral Particle
SKU
RC202667L2V
Lenti ORF particles, KLK2 (mGFP-tagged) - Human kallikrein-related peptidase 2 (KLK2), transcript variant 1, 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | Kallikrein 2 |
Synonyms | hGK-1; hK2; KLK2A2 |
Vector | pLenti-C-mGFP |
Mammalian Cell Selection | None |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC202667).
|
ACCN | NM_005551 |
ORF Size | 783 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_005551.3 |
RefSeq Size | 2855 bp |
RefSeq ORF | 786 bp |
Locus ID | 3817 |
UniProt ID | P20151 |
Cytogenetics | 19q13.33 |
Domains | Tryp_SPc |
Protein Families | Druggable Genome, Protease |
MW | 28.7 kDa |
Summary | This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012] |
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