EZH1 (NM_001991) Human Tagged ORF Clone Lentiviral Particle
SKU
RC202367L4V
Lenti ORF particles, EZH1 (mGFP-tagged) - Human enhancer of zeste homolog 1 (Drosophila) (EZH1), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | EZH1 |
Synonyms | KMT6B |
Vector | pLenti-C-mGFP-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC202367).
|
ACCN | NM_001991 |
ORF Size | 2241 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_001991.2 |
RefSeq Size | 4640 bp |
RefSeq ORF | 2244 bp |
Locus ID | 2145 |
UniProt ID | Q92800 |
Cytogenetics | 17q21.2 |
Domains | myb_DNA-binding, SET |
Protein Families | Druggable Genome, Transcription Factors |
MW | 85.1 kDa |
Summary | EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMed 19026780]).[supplied by OMIM, Mar 2009] |
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