PGD (NM_002631) Human Tagged ORF Clone Lentiviral Particle

SKU RC201729L3V

Lenti ORF particles, PGD (Myc-DDK tagged) - Human phosphogluconate dehydrogenase (PGD), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: PGD
• Synonyms: 6PGD
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201729).
• ACCN: NM_002631
• ORF Size: 1449 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_002631.2
• RefSeq Size: 1937 bp
• RefSeq ORF: 1452 bp
• Locus ID: 5226
• UniProt ID: P52209
• Cytogenetics: 1p36.22
• Domains: 6PGD, NAD_binding_2
• Protein Pathways: Glutathione metabolism, Metabolic pathways, Pentose phosphate pathway
• MW: 53.1 kDa
• Summary: 6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015]