APPBP1 (NAE1) (NM_001018160) Human Tagged ORF Clone Lentiviral Particle

SKU RC201326L3V

Lenti ORF particles, NAE1 (Myc-DDK tagged) - Human NEDD8 activating enzyme E1 subunit 1 (NAE1), transcript variant 3, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: APPBP1
• Synonyms: A-116A10.1; APPBP1; HPP1; ula-1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201326).
• ACCN: NM_001018160
• ORF Size: 1602 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001018160.1
• RefSeq Size: 1716 bp
• RefSeq ORF: 1338 bp
• Locus ID: 8883
• UniProt ID: Q13564
• Cytogenetics: 16q22.1
• Protein Pathways: Alzheimer's disease
• MW: 60.2 kDa
• Summary: The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]