Exonuclease 1 (EXO1) (NM_130398) Human Tagged ORF Clone Lentiviral Particle

SKU RC200547L3V

Lenti ORF particles, EXO1 (Myc-DDK tagged) - Human exonuclease 1 (EXO1), transcript variant 2, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Exonuclease 1
• Synonyms: HEX1; hExoI
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200547).
• ACCN: NM_130398
• ORF Size: 2538 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_130398.2, NP_569082.1
• RefSeq Size: 3478 bp
• RefSeq ORF: 2541 bp
• Locus ID: 9156
• UniProt ID: Q9UQ84
• Cytogenetics: 1q43
• Domains: XPG_I, XPG_N
• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: Mismatch repair
• MW: 94 kDa
• Summary: This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms. [provided by RefSeq, Jul 2008]