LDOC1 (NM_012317) Human Tagged ORF Clone Lentiviral Particle
SKU
RC200543L4V
Lenti ORF particles, LDOC1 (mGFP-tagged) - Human leucine zipper, down-regulated in cancer 1 (LDOC1), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | LDOC1 |
Synonyms | BCUR1; Mar7; Mart7; RTL7; SIRH7 |
Vector | pLenti-C-mGFP-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC200543).
|
ACCN | NM_012317 |
ORF Size | 438 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_012317.2 |
RefSeq Size | 1470 bp |
RefSeq ORF | 441 bp |
Locus ID | 23641 |
UniProt ID | O95751 |
Cytogenetics | Xq27.1 |
MW | 17 kDa |
Summary | The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers. [provided by RefSeq, Jul 2008] |
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