LOXL2 (NM_002318) Human Tagged ORF Clone Lentiviral Particle

SKU RC200455L3V

Lenti ORF particles, LOXL2 (Myc-DDK tagged) - Human lysyl oxidase-like 2 (LOXL2), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: LOXL2
• Synonyms: LOR; LOR2; WS9-14
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200455).
• ACCN: NM_002318
• ORF Size: 2322 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_002318.2
• RefSeq Size: 3810 bp
• RefSeq ORF: 2325 bp
• Locus ID: 4017
• UniProt ID: Q9Y4K0
• Cytogenetics: 8p21.3
• Domains: Lysyl_oxidase, SR
• Protein Families: Druggable Genome, Secreted Protein
• MW: 86.7 kDa
• Summary: This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]