nSMase (SMPD2) (NM_003080) Human Tagged ORF Clone Lentiviral Particle

SKU RC200417L4V

Lenti ORF particles, SMPD2 (mGFP-tagged) - Human sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) (SMPD2), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: nSMase
• Synonyms: ISC1; NSMASE; NSMASE1
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200417).
• ACCN: NM_003080
• ORF Size: 1269 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_003080.2
• RefSeq Size: 1697 bp
• RefSeq ORF: 1272 bp
• Locus ID: 6610
• UniProt ID: O60906
• Cytogenetics: 6q21
• Domains: Exo_endo_phos
• Protein Families: Transmembrane
• Protein Pathways: Metabolic pathways, Sphingolipid metabolism
• MW: 47.6 kDa
• Summary: This gene encodes a protein which was initially identified as a sphingomyelinase based on sequence similarity between bacterial sphingomyelinases and a yeast protein. Subsequent studies showed that its biological function is less likely to be as a sphingomyelinase and instead as a lysophospholipase. [provided by RefSeq, Oct 2009]