ATG4B (NM_013325) Human Tagged ORF Clone Lentiviral Particle

SKU RC200289L3V

Lenti ORF particles, ATG4B (Myc-DDK tagged) - Human ATG4 autophagy related 4 homolog B (S. cerevisiae) (ATG4B), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: ATG4B
• Synonyms: APG4B; AUTL1
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200289).
• ACCN: NM_013325
• ORF Size: 1179 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_013325.4
• RefSeq Size: 2892 bp
• RefSeq ORF: 1182 bp
• Locus ID: 23192
• UniProt ID: Q9Y4P1
• Cytogenetics: 2q37.3
• Domains: Peptidase_C54
• Protein Families: Protease
• Protein Pathways: Regulation of autophagy
• MW: 44.3 kDa
• Summary: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]