Calnexin (CANX) (NM_001746) Human Tagged ORF Clone Lentiviral Particle
SKU
RC200229L3V
Lenti ORF particles, CANX (Myc-DDK tagged) - Human calnexin (CANX), transcript variant 1, 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | Myc-DDK |
Target Symbol | Calnexin |
Synonyms | CNX; IP90; P90 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC200229).
|
ACCN | NM_001746 |
ORF Size | 1776 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_001746.3 |
RefSeq Size | 4953 bp |
RefSeq ORF | 1779 bp |
Locus ID | 821 |
UniProt ID | P27824 |
Cytogenetics | 5q35.3 |
Domains | calreticulin |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Antigen processing and presentation |
MW | 67.6 kDa |
Summary | This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2018] |
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