Bmpr1a (NM_009758) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR227586L3V

Lenti ORF particles, Bmpr1a (Myc-DDK-tagged) - Mouse bone morphogenetic protein receptor, type 1A (Bmpr1a), 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Bmpr1a
• Synonyms: 1110037I22Rik; ALK3; AU045487; Bmpr; BMPR-IA
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR227586).
• ACCN: NM_009758
• ORF Size: 1596 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_009758.4, NP_033888.2
• RefSeq Size: 5481 bp
• RefSeq ORF: 1599 bp
• Locus ID: 12166
• UniProt ID: P36895
• Cytogenetics: 14 20.81 cM
• Summary: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction (PubMed:24098149). Mediates induction of adipogenesis by GDF6 (PubMed:23527555).[UniProtKB/Swiss-Prot Function]