Il4ra (NM_001008700) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR227371L3V

Lenti ORF particles, Il4ra (Myc-DDK-tagged) - Mouse interleukin 4 receptor, alpha (Il4ra), 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Il4ra
• Synonyms: CD124; Il4r
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR227371).
• ACCN: NM_001008700
• ORF Size: 2430 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001008700.3
• RefSeq Size: 5122 bp
• RefSeq ORF: 2433 bp
• Locus ID: 16190
• UniProt ID: P16382
• Cytogenetics: 7 68.94 cM
• Summary: Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.[UniProtKB/Swiss-Prot Function]