P2rx7 (NM_011027) Mouse Tagged ORF Clone Lentiviral Particle
SKU
MR227216L4V
Lenti ORF particles, P2rx7 (GFP-tagged) - Mouse purinergic receptor P2X, ligand-gated ion channel, 7 (P2rx7), transcript variant 1, 200ul, >10^7 TU/mL
Product Data | |
Type | Mouse Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | P2rx7 |
Synonyms | AI467586; P2X(7); P2X7R |
Vector | pLenti-C-mGFP-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(MR227216).
|
ACCN | NM_011027 |
ORF Size | 1785 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_011027.2 |
RefSeq Size | 4931 bp |
RefSeq ORF | 1788 bp |
Locus ID | 18439 |
UniProt ID | Q9Z1M0 |
Cytogenetics | 5 F |
Summary | Receptor for ATP that acts as a ligand-gated ion channel. Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells. In the absence of its natural ligand, ATP, functions as a scavenger receptor in the recognition and engulfment of apoptotic cells.[UniProtKB/Swiss-Prot Function] |
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