Ptpra (NM_008980) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR226249L3V

Lenti ORF particles, Ptpra (Myc-DDK-tagged) - Mouse protein tyrosine phosphatase, receptor type, A (Ptpra), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Ptpra
• Synonyms: Ptpa; Ptpalpha; Rptpalpha; Rptra; Rptralpha
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR226249).
• ACCN: NM_008980
• ORF Size: 2487 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_008980.2, NP_033006.2
• RefSeq Size: 3609 bp
• RefSeq ORF: 2490 bp
• Locus ID: 19262
• UniProt ID: P18052
• Cytogenetics: 2 63.23 cM
• Summary: Tyrosine protein phosphatase which is involved in integrin-mediated focal adhesion formation (PubMed:22801373). Following integrin engagement, specifically recruits BCAR3, BCAR1 and CRK to focal adhesions thereby promoting SRC-mediated phosphorylation of BRAC1 and the subsequent activation of PAK and small GTPase RAC1 and CDC42 (PubMed:22801373).[UniProtKB/Swiss-Prot Function]