As3mt (NM_020577) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR225259L3V

Lenti ORF particles, As3mt (Myc-DDK-tagged) - Mouse arsenic (+3 oxidation state) methyltransferase (As3mt), 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: As3mt
• Synonyms: 2310045H08Rik; Cyt19
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR225259).
• ACCN: NM_020577
• ORF Size: 1128 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_020577.2, NP_065602.2
• RefSeq Size: 1752 bp
• RefSeq ORF: 1131 bp
• Locus ID: 57344
• UniProt ID: Q91WU5
• Cytogenetics: 19 C3
• Summary: Catalyzes the transfer of a methyl group from AdoMet to trivalent arsenicals producing methylated and dimethylated arsenicals. It methylates arsenite to form methylarsonate, Me-AsO(3)H(2), which is reduced by methylarsonate reductase to methylarsonite, Me-As(OH)2. Methylarsonite is also a substrate and it is converted into the much less toxic compound dimethylarsinate (cacodylate), Me(2)As(O)-OH.[UniProtKB/Swiss-Prot Function]