Dcstamp (NM_029422) Mouse Tagged ORF Clone Lentiviral Particle
SKU
MR224544L4V
Lenti ORF particles, Dcstamp (GFP-tagged) - Mouse transmembrane 7 superfamily member 4 (Tm7sf4), 200ul, >10^7 TU/mL
Product Data | |
Type | Mouse Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | Dcstamp |
Synonyms | 4833414I07Rik; DC-STAMP; FIND; mDC-STAMP; Tm7sf4 |
Vector | pLenti-C-mGFP-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(MR224544).
|
ACCN | NM_029422 |
ORF Size | 1410 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_029422.3, NP_083698.1 |
RefSeq Size | 1993 bp |
RefSeq ORF | 1413 bp |
Locus ID | 75766 |
UniProt ID | Q7TNJ0 |
Cytogenetics | 15 B3.1 |
Summary | Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis. Plays a role in TNFSF11-mediated osteoclastogenesis. Cooperates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Participates in osteoclast bone resorption. Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors. Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage. Inhibits the development of neutrophilic granulocytes. Plays also a role in the regulation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity. Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions.[UniProtKB/Swiss-Prot Function] |
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