Itgae (NM_008399) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR224278L4V

Lenti ORF particles, Itgae (GFP-tagged) - Mouse integrin alpha E, epithelial-associated (Itgae), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Itgae
• Synonyms: A530055J10; alpha-E1; alpha-M290; aM290; CD103
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR224278).
• ACCN: NM_008399
• ORF Size: 3501 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_008399.2
• RefSeq Size: 3836 bp
• RefSeq ORF: 3504 bp
• Locus ID: 16407
• UniProt ID: Q60677
• Cytogenetics: 11 45.22 cM
• Summary: Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. Mice expressing a null mutation of the alpha-E subunit gene exhibit a marked reduction in the numbers of intraepithelial lymphocytes in the gut and in the development of gut-associated lymphoid aggregates, supporting a specific role for this integrin in mediating retention of lymphocytes in the intestinal wall.[UniProtKB/Swiss-Prot Function]