Npas1 (NM_008718) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR222175L3V

Lenti ORF particles, Npas1 (Myc-DDK-tagged) - Mouse neuronal PAS domain protein 1 (Npas1), 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Npas1
• Synonyms: bHLHe11; MOP5
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR222175).
• ACCN: NM_008718
• ORF Size: 1782 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_008718.2, NP_032744.1
• RefSeq Size: 2091 bp
• RefSeq ORF: 1785 bp
• Locus ID: 18142
• UniProt ID: P97459
• Cytogenetics: 7 9.14 cM
• Summary: May control regulatory pathways relevant to schizophrenia and to psychotic illness. May play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen level. Forms a heterodimer that binds core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) leading to transcriptional repression on its target gene TH (PubMed:27782878).[UniProtKB/Swiss-Prot Function]