Rreb1 (NM_001177868) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR219806L4V

Lenti ORF particles, Rreb1 (GFP-tagged) - Mouse ras responsive element binding protein 1 (Rreb1), transcript variant 4, 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Rreb1
• Synonyms: 1110037N09Rik; AA414966; B930013M22Rik
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR219806).
• ACCN: NM_001177868
• ORF Size: 3873 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001177868.1, NP_001171339.1
• RefSeq Size: 7198 bp
• RefSeq ORF: 3876 bp
• Locus ID: 68750
• UniProt ID: Q3UH06
• Cytogenetics: 13 A3.3
• Summary: Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1 (By similarity). Binds specifically to the allelic variant of the CDKN2A promoter present in Balb/c mice, which leads to a down-regulation of CDKN2A expression in this strain, and, as a consequence, to an elevated susceptibility to pristane-induced tumors.[UniProtKB/Swiss-Prot Function]