Cyfip2 (NM_133769) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR217769L3V

Lenti ORF particles, Cyfip2 (Myc-DDK-tagged) - Mouse cytoplasmic FMR1 interacting protein 2 (Cyfip2), 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Cyfip2
• Synonyms: 1500004I01Rik; 6430511D02Rik; AA930218; AU022376; mKIAA1168; Pir121
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR217769).
• ACCN: NM_133769
• ORF Size: 3759 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_133769.3, NP_598530.2
• RefSeq Size: 6352 bp
• RefSeq ORF: 3762 bp
• Locus ID: 76884
• UniProt ID: Q5SQX6
• Cytogenetics: 11 B1.1
• Summary: Part of the WAVE1 complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex (By similarity). Involved in T-cell adhesion and p53-dependent induction of apoptosis (By similarity). Does not bind RNA. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (PubMed:27605705).[UniProtKB/Swiss-Prot Function]