Smg6 (NM_001002764) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR211977L3V

Lenti ORF particles, Smg6 (Myc-DDK-tagged) - Mouse Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans) (Smg6), 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Smg6
• Synonyms: AI317223; AU041178
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR211977).
• ACCN: NM_001002764
• ORF Size: 4254 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001002764.1
• RefSeq Size: 5817 bp
• RefSeq ORF: 4257 bp
• Locus ID: 103677
• UniProt ID: P61406
• Cytogenetics: 11 B5
• Summary: Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. May have a general role in telomere regulation. Promotes in vitro the ability of TERT to elongate telomeres. Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization. Binds to the single-stranded 5'-(GTGTGG)(4)GTGT-3' telomeric DNA, but not to a telomerase RNA template component (TER).[UniProtKB/Swiss-Prot Function]