Kcnn4 (NM_008433) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR206777L4V

Lenti ORF particles, Kcnn4 (GFP-tagged) - Mouse potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4 (Kcnn4), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Kcnn4
• Synonyms: IK1; IKCA1; KCa3.1; KCA4; mIKCa1; SK4; SKCas
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR206777).
• ACCN: NM_008433
• ORF Size: 1275 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_008433.2, NP_032459.2
• RefSeq Size: 1956 bp
• RefSeq ORF: 1278 bp
• Locus ID: 16534
• UniProt ID: O89109
• Cytogenetics: 7 A3
• Summary: Forms a voltage-independent potassium channel that is activated by intracellular calcium (PubMed:9705284). Activation is followed by membrane hyperpolarization which promotes calcium influx. Required for maximal calcium influx and proliferation during the reactivation of naive T-cells (PubMed:20884616). Plays a role in the late stages of EGF-induced macropinocytosis (By similarity).[UniProtKB/Swiss-Prot Function]