Hmox1 (NM_010442) Mouse Tagged ORF Clone Lentiviral Particle
SKU
MR203944L2V
Lenti ORF particles, Hmox1 (GFP-tagged) - Mouse heme oxygenase (decycling) 1 (Hmox1), 200ul, >10^7 TU/mL
Product Data | |
Type | Mouse Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | Hmox1 |
Synonyms | D8Wsu38e; Hemox; Hmox; HO-1; HO1; Hsp32 |
Vector | pLenti-C-mGFP |
Mammalian Cell Selection | None |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(MR203944).
|
ACCN | NM_010442 |
ORF Size | 867 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_010442.1 |
RefSeq Size | 1564 bp |
RefSeq ORF | 870 bp |
Locus ID | 15368 |
UniProt ID | P14901 |
Cytogenetics | 8 C1 |
Summary | Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.[UniProtKB/Swiss-Prot Function] |
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