Ppp1r3b (NM_177741) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR203867L3V

Lenti ORF particles, Ppp1r3b (Myc-DDK-tagged) - Mouse protein phosphatase 1, regulatory (inhibitor) subunit 3B (Ppp1r3b), 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Ppp1r3b
• Synonyms: 6430576E21; AW821953; GL; PTG
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR203867).
• ACCN: NM_177741
• ORF Size: 852 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_177741.3
• RefSeq Size: 4229 bp
• RefSeq ORF: 855 bp
• Locus ID: 244416
• UniProt ID: Q8C767
• Cytogenetics: 8 A4
• Summary: Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes (By similarity).[UniProtKB/Swiss-Prot Function]