Rnf186 (NM_025786) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR202649L4V

Lenti ORF particles, Rnf186 (GFP-tagged) - Mouse ring finger protein 186 (Rnf186), 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Rnf186
• Synonyms: 9130020G10Rik
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR202649).
• ACCN: NM_025786
• ORF Size: 678 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_025786.2, NP_080062.3
• RefSeq Size: 1273 bp
• RefSeq ORF: 843 bp
• Locus ID: 66825
• UniProt ID: Q9D241
• Cytogenetics: 4 D3
• Summary: E3 ubiquitin protein ligase that is part of an apoptotic signaling pathway activated by endoplasmic reticulum stress. In that process, stimulates the expression of proteins specific of the unfolded protein response (UPR), ubiquitinates BNIP1 and regulates its localization to the mitochondrion and induces calcium release from the endoplasmic reticulum that ultimately leads to cell apoptosis.[UniProtKB/Swiss-Prot Function]