Ppp1r11 (NM_029632) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR200757L3V

Lenti ORF particles, Ppp1r11 (Myc-DDK-tagged) - Mouse protein phosphatase 1, regulatory (inhibitor) subunit 11 (Ppp1r11), 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: Myc-DDK
• Target Symbol: Ppp1r11
• Synonyms: 1500041B02Rik; AV117883; Hcgv; Tcte5; Tctex-5; Tctex5
• Vector: pLenti-C-Myc-DDK-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR200757).
• ACCN: NM_029632
• ORF Size: 393 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_029632.3, NP_083908.1
• RefSeq Size: 1696 bp
• RefSeq ORF: 396 bp
• Locus ID: 76497
• UniProt ID: Q8K1L5
• Cytogenetics: 17 19.16 cM
• Summary: Atypical E3 ubiquitin-protein ligase which ubiquitinates TLR2 at 'Lys-754' leading to its degradation by the proteasome. Plays a role in regulating inflammatory cytokine release and gram-positive bacterial clearance by functioning, in part, through the ubiquitination and degradation of TLR2 (PubMed:27805901). Inhibitor of protein phosphatase 1 (By similarity).[UniProtKB/Swiss-Prot Function]