NRXN3 (NM_001272020) Human Untagged Clone

SKU SC331024

NRXN3 (untagged) - Homo sapiens neurexin 3 (NRXN3), transcript variant 4

Product Data

• Type: Human Untagged Clone
• Target Symbol: NRXN3
• Synonyms: C14orf60
• Vector: pCMV6-Entry
• Sequence Data:
  Fully Sequenced ORF

  >SC331024 representing NM_001272020.; Blue=Insert sequence Red=Cloning site Green=Tag(s); ; ATGCACCTGAGAATCCACGCGAGACGGAGCCCTCCTCGCCGGCCGGCCTGGACGCTTGGGATCTGGTTC; CTGTTCTGGGGATGTATCGTCAGCTCTGTATGGAGTTCTTCTAATGTAGCTTCCTCCTCCTCCACCTCT; TCCTCGCCGGGGTCTCACTCTCAGCACGAGCACCATTTCCATGGCAGCAAGCATCACTCAGTGCCTATT; TCTATCTATCGTTCCCCTGTTTCCCTTCGAGGAGGACACGCTGGCGCTACGTACATCTTTGGGAAAAGT; GGTGGGCTTATCCTCTACACCTGGCCAGCCAATGACAGGCCCAGCACGCGGTCTGACCGCCTTGCCGTG; GGCTTCAGCACCACTGTGAAGGATGGCATCTTGGTCCGCATCGACAGTGCTCCAGGACTTGGTGACTTC; CTCCAGCTTCACATAGAACAGGGGAAAATTGGAGTTGTCTTCAACATTGGCACAGTTGACATCTCCATC; AAAGAGGAGAGAACCCCTGTAAATGACGGCAAATACCATGTGGTACGCTTCACCAGGAACGGCGGCAAC; GCCACCCTGCAGGTGGACAACTGGCCAGTGAATGAACATTATCCTACAGGCCGGCAGTTAACCATCTTC; AACACTCAGGCGCAAATAGCCATTGGTGGAAAGGACAAAGGACGCCTCTTCCAAGGCCAACTCTCTGGG; CTCTATTATGATGGTTTGAAAGTACTGAACATGGCGGCTGAGAACAACCCCAATATTAAAATCAATGGA; AGTGTTCGGCTGGTTGGAGAAGTCCCATCAATTTTGGGAACAACACAGACGACCTCCATGCCACCAGAA; ATGTCTACTACTGTCATGGAAACCACTACTACAATGGCGACTACCACAACCCGTAAGAATCGCTCTACA; GCCAGCATTCAGCCAACATCAGATGATCTTGTTTCATCTGCTGAATGTTCAAGTGATGATGAAGACTTT; GTTGAATGTGAGCCGAGTACAGGAGGTGAATTAGTTATCCCTCTTCTTGTAGAAGACCCTTTAGCTACC; CCTCCTATTGCTACTCGTGCACCTTCCATTACACTCCCCCCTACCTTTCGCCCCCTCCTCACCATTATT; GAGACCACCAAAGATTCCCTGTCCATGACCTCTGAGGCGGGGTTACCTTGCTTGTCGGACCAAGGCAGC; GATGGTTGTGATGATGATGGCTTGGTGATATCTGGGTATGGCTCAGGGGAAACCTTTGACTCTAACCTG; CCCCCTACTGATGATGAAGATTTTTACACCACCTTCTCCTTGGTAACAGATAAGAGTCTTTCCACTTCA; ATCTTCGAAGGTGGCTACAAAGCACATGCGCCCAAGTGGGAATCCAAGGACTTTAGACCTAACAAAGTC; TCCGAAACTAGTAGGACTACTACCACATCTTTATCCCCTGAGCTGATCCGCTTCACAGCTTCCTCCTCG; TCTGGGATGGTGCCCAAATTGCCAGCTGGCAAAATGAATAACCGTGATCTCAAACCCCAGCCTGATATA; GTCTTGCTTCCGTTGCCCACTGCCTATGAGCTAGACAGCACCAAACTGAAGAGCCCACTAATTACTTCC; CCCATGTTCCGTAATGTGCCCACAGCAAACCCCACGGAGCCGGGAATCAGACGGGTTCCGGGGGCCTCA; GAGGTGATCCGGGAGTCGAGCAGCACAACAGGGATGGTCGTCGGCATTGTGGCTGCTGCCGCCCTCTGC; ATCTTGATCCTCCTGTACGCCATGTACAAGTACAGGAACAGGGACGAGGGGTCCTATCAAGTGGACGAG; ACGCGGAACTACATCAGCAACTCCGCCCAGAGCAACGGCACGCTCATGAAGGAGAAGCAGCAGAGCTCG; AAGAGCGGCCACAAGAAACAGAAAAACAAGGACAGGGAGTATTACGTGTAA;
• Restriction Sites: SgfI-MluI
• ACCN: NM_001272020
• Insert Size: 1914 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001272020.1
• RefSeq Size: 9193 bp
• RefSeq ORF: 1914 bp
• Locus ID: 9369
• UniProt ID: Q9HDB5
• Cytogenetics: 14q24.3-q31.1
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)
• MW: 69.3 kDa
• Summary: This gene encodes a member of a family of proteins that function in the nervous system as receptors and cell adhesion molecules. Extensive alternative splicing and the use of alternative promoters results in multiple transcript variants and protein isoforms for this gene, but the full-length nature of many of these variants has not been determined. Transcripts that initiate from an upstream promoter encode alpha isoforms, which contain epidermal growth factor-like (EGF-like) sequences and laminin G domains. Transcripts initiating from the downstream promoter encode beta isoforms, which lack EGF-like sequences. Genetic variation at this locus has been associated with a range of behavioral phenotypes, including alcohol dependence and autism spectrum disorder. [provided by RefSeq, Dec 2012]; Transcript Variant: This variant (4) differs in the 5' UTR and contains multiple differences in the coding region, including the lack of multiple 5' exons, compared to variant 1. It initiates translation at an alternate start codon. The encoded isoform (4) is shorter and has a distinct N-terminus, compared to isoform 1. This variant encodes a beta isoform. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.