SFXN3 (NM_030971) Human Untagged Clone

CAT#: SC321564

SFXN3 (untagged)-Human sideroflexin 3 (SFXN3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SFXN3
• Synonyms: BA108L7.2; SFX3; SLC56A3
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_030971.3 GGAGGGCCCGGCGGCGACAGCGGAGGCAGAGAGGAAGGCGGTTCTGAGAGCTTCAGAGAG
  CGATGGAAAGCAAAATGGGTGAATTGCCTTTAGACATCAACATCCAGGAACCTCGCTGGG
  ACCAAAGTACTTTCCTGGGCAGAGCCCGGCACTTTTTCACTGTTACTGATCCTCGAAATC
  TGCTGCTGTCCGGGGCACAGCTGGAAGCTTCTCGGAACATCGTGCAGAACTACAGGGCCG
  GCGTGGTGACCCCAGGGATCACCGAGGACCAGCTGTGGAGGGCCAAGTATGTGTATGACT
  CCGCCTTCCATCCGGACACAGGGGAGAAGGTGGTCCTGATTGGCCGCATGTCAGCCCAGG
  TGCCCATGAACATGACCATCACTGGCTGCATGCTCACATTCTACAGGAAGACCCCAACCG
  TGGTGTTCTGGCAGTGGGTGAATCAGTCCTTCAATGCCATTGTTAACTACTCCAACCGCA
  GTGGTGACACTCCCATCACTGTGAGGCAGCTGGGGACAGCCTATGTGAGTGCCACCACTG
  GAGCTGTGGCCACGGCCCTGGGACTCAAATCCCTCACCAAGCACCTGCCCCCCTTGGTCG
  GCAGATTTGTGCCCTTTGCAGCAGTGGCAGCTGCCAACTGCATCAACATCCCCCTGATGA
  GGCAGAGAGAGCTGCAGGTGGGCATCCCGGTGGCTGATGAGGCAGGTCAGAGGCTTGGCT
  ACTCGGTGACTGCAGCCAAGCAGGGAATCTTCCAGGTGGTGATTTCAAGAATCTGCATGG
  CGATTCCTGCCATGGCCATCCCACCACTGATCATGGACACTCTGGAGAAGAAAGACTTCC
  TGAAGCGCCGCCCCTGGCTGGGGGCACCCCTGCAGGTGGGACTGGTGGGCTTCTGCCTGG
  TATTTGCAACCCCCCTGTGCTGTGCCCTATTCCCCCAGAAGAGCTCCATACACATAAGCA
  ACCTGGAACCAGAGCTGAGAGCTCAGATCCATGAGCAAAACCCCAGCGTTGAAGTGGTCT
  ACTACAACAAGGGGCTTTGAGGAGGGTCAGCCTCTGTCCCCTCCCTCACTTCCTTGGGCT
  GCTGCTTTAGTGGAGTCATGTCACCCCTACCACTTGGCTATCTGCCTAGCACTGGGCAGG
  GGCCTTGGTGGGCAGATGGCAATTGAGGGTAGCAACCTATTAGGGTGGGGGAGGGACCTC
  CATAAGGCTTTTCCTCCCTTCTCTGGTTTCAAAGATCAGAGCACATAACCCCTCCTGTGC
  TTGAGTGTCCATGCATATACATACATGATACACATGTGTATGTGTACATTGGGTCCTGAA
  AGCTAGAAGCAGGCATGCTAGCCTAGTATGTTCTGACATCTGGCTTCCCTTCTCAGCCTC
  ATGTCCACCTGCCTGCCAGCCAGGCTACAGGTGTGACTTCCTTCTCTAAACTGTTACACC
  AGCCAAGTTATTTTTGATGGCACCTCATCCCTTCTAGAAATAGGAGGAGCCCCAGGATCT
  CAGGACAGAGACTTATAGACACTAGTAGGACAAAGCGGGCTGAATCCTTCAGGTTTCTGA
  TACCTAGCTCCCCAAGCTGACTGGGCTGGCAGAGGAGAACATGTTGAGACAAGGGAGGCA
  GGGGACTTATGCATCCCTCAGTGCCATCCCTTGTATCCTGGAATAGCTCCATTTCCCCTC
  CTCCTCTCTACCAGACAAAGGAGTGCCTGTGTCCTGTACTGCCCTCGCTGTCTCCCCCAC
  CACCCTACTTGACAGCGTGGGCATCTTCAGGCACAGCCTTGGGAGTTCCTGGTGTGCTCT
  GACATCATGACCTCAAATCTAAATCCTCCAATCCCAACTCCCTTTCCCAAACAAAAAGCC
  ACAGAGGCAGAGCAAGCATTCCCCTTTAAGAGCTTCCACTGCACCCCCTCCCAAGGGACA
  CAGCGGTAGGAATGGTGCTTAAACTCCACAGGTATCAGAGAGGGTGTAACTAGGACATCC
  TCAAGGGCAGCTAGGCCCCGAATGTACAATGTTAAGACAGGGAATTTTGTGTTCCATTGA
  CTTTTTTTTTTTTTTTTAATGGAGTTTCACTATTTTGCCCAGGCTGGAGTGCGATGGTGC
  GATCTTGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGTGATTCTCTTGCCTCAGTCTC
  CCGAGTAGTGGAAATTACAGGTGTGTGCTACCACATCTTGCTAGTTTTGTATTTTTAGCA
  GAGATGGGGGTTTCACCATGTTGGCCAGGCTAGTCTCGAACTCCTGACCTCAGGTGATCC
  ACCTGCCTTGGCCTCCCAAAGCACTGGGATTACAAGCATGAGCCACTGTGCCCAGCCTGT
  TCCACTGACATTTCTTAGACATTCAGCAAAACCCCCACCTTAACCTCTTTTCTTTCTTGA
  GGGTTGGTCCTGTCCCCACCTCCACCCTCCCACCCCCTGGAAGAGGAAGGGCCCGGGCAT
  CAGTGGCTAGTCCAAATAAAATATGGGCTTGGGGATGGAATGGGTGGTGGTAAGTTCACA
  GAGTGTAGTTAGATCCCAACTCCCATGACCTCTGGCTTCAGTGGTGGGTGGGGCAGGGCA
  GATGAAAGGGCTTCAGTGGGAACCTCTGAGAGCATTTTCCTGTTCCCCCTATCAACCGCC
  CCCAGTGATAACATCTGTGAAGCCAGCCATTACTCAATAAACTGCAAACTTGTCTAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_030971
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_030971.3, NP_112233.2
• RefSeq Size: 3129 bp
• RefSeq ORF: 978 bp
• Locus ID: 81855
• UniProt ID: Q9BWM7
• Cytogenetics: 10q24.31
• Domains: Mtc
• Protein Families: Transmembrane
• Gene Summary: Mitochondrial serine transporter that mediates transport of serine into mitochondria, an important step of the one-carbon metabolism pathway (PubMed:30442778). Mitochondrial serine is converted to glycine and formate, which then exits to the cytosol where it is used to generate the charged folates that serve as one-carbon donors (PubMed:30442778).[UniProtKB/Swiss-Prot Function]