IFNGR1 (NM_000416) Human Untagged Clone

CAT#: SC321055

IFNGR1 (untagged)-Human interferon gamma receptor 1 (IFNGR1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IFNGR1
• Synonyms: CD119; IFNGR; IMD27A; IMD27B
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_000416.1 GACGTAAGGCCGGGGCTGGAGGGCAGTGCTGGGCTGGTCCCGCAGGCGCTCGGGGTTGGA
  GCCAGCGACCGTCGGTAGCAGCATGGCTCTCCTCTTTCTCCTACCCCTTGTCATGCAGGG
  TGTGAGCAGGGCTGAGATGGGCACCGCGGATCTGGGGCCGTCCTCAGTGCCTACACCAAC
  TAATGTTACAATTGAATCCTATAACATGAACCCTATCGTATATTGGGAGTACCAGATCAT
  GCCACAGGTCCCTGTTTTTACCGTAGAGGTAAAGAACTATGGTGTTAAGAATTCAGAATG
  GATTGATGCCTGCATCAATATTTCTCATCATTATTGTAATATTTCTGATCATGTTGGTGA
  TCCATCAAATTCTCTTTGGGTCAGAGTTAAAGCCAGGGTTGGACAAAAAGAATCTGCCTA
  TGCAAAGTCAGAAGAATTTGCTGTATGCCGAGATGGAAAAATTGGACCACCTAAACTGGA
  TATCAGAAAGGAGGAGAAGCAAATCATGATTGACATATTTCACCCTTCAGTTTTTGTAAA
  TGGAGACGAGCAGGAAGTCGATTATGATCCCGAAACTACCTGTTACATTAGGGTGTACAA
  TGTGTATGTGAGAATGAACGGAAGTGAGATCCAGTATAAAATACTCACGCAGAAGGAAGA
  TGATTGTGACGAGATTCAGTGCCAGTTAGCGATTCCAGTATCCTCACTGAATTCTCAGTA
  CTGTGTTTCAGCAGAAGGAGTCTTACATGTGTGGGGTGTTACAACTGAAAAGTCAAAAGA
  AGTTTGTATTACCATTTTCAATAGCAGTATAAAAGGTTCTCTTTGGATTCCAGTTGTTGC
  TGCTTTACTACTCTTTCTAGTGCTTAGCCTGGTATTCATCTGTTTTTATATTAAGAAAAT
  TAATCCATTGAAGGAAAAAAGCATAATATTACCCAAGTCCTTGATCTCTGTGGTAAGAAG
  TGCTACTTTAGAGACAAAACCTGAATCAAAATATGTATCACTCATCACGTCATACCAGCC
  ATTTTCCTTAGAAAAGGAGGTGGTCTGTGAAGAGCCGTTGTCTCCAGCAACAGTTCCAGG
  CATGCATACCGAAGACAATCCAGGAAAAGTGGAACATACAGAAGAACTTTCTAGTATAAC
  AGAAGTGGTGACTACTGAAGAAAATATTCCTGACGTGGTCCCGGGCAGCCATCTGACTCC
  AATAGAGAGAGAGAGTTCTTCACCTTTAAGTAGTAACCAGTCTGAACCTGGCAGCATCGC
  TTTAAACTCGTATCACTCCAGAAATTGTTCTGAGAGTGATCACTCCAGAAATGGTTTTGA
  TACTGATTCCAGCTGTCTGGAATCACATAGCTCCTTATCTGACTCAGAATTTCCCCCAAA
  TAATAAAGGTGAAATAAAAACAGAAGGACAAGAGCTCATAACCGTAATAAAAGCCCCCAC
  CTCCTTTGGTTATGATAAACCACATGTGCTAGTGGATCTACTTGTGGATGATAGCGGTAA
  AGAGTCCTTGATTGGTTATAGACCAACAGAAGATTCCAAAGAATTTTCATGAGATCAGCT
  AAGTTGCACCAACTTTGAAGTCTGATTTTCCTGGACAGTTTTCTGCTTTAATTTCATGAA
  AAGATTATGATCTCAGAAATTGTATCTTAGTTGGTATCAACCAAATGGAGTGACTTAGTG
  TACATGAAAGCGTAAAGAGGATGTGTGGCATTTTCACTTTTGGCTTGTAAAGTACAGACT
  TTTTTTTTTTTTTTAAACAAAAAAAGCATTGTAACTTATGAACCTTTACATCCAGATAGG
  TTACCAGTAACGGAACAGTATCCAGTACTCCTGGTCCCTAGGTGAGCAGGTGATGCCCCA
  GGGACCTTTGTAGCCACTTCACTTTTTTTTCTTTTCTCTGCCTTGGTATAGCATATGTTT
  TTGTAAGTTTATGCATACAGTAATTTTAAGTAATTTCAGAAGAAATTCTGCAAGCTTTTC
  AAAATTGGACTTAAAATCTAATTCAAACTAATAGAATTAATGGAATATGTAAATAGAAAC
  GTGTATATTTTTTATGAAACATTACAGTTAGAGATTTTTAAATAAAGAATTTTAAAACAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_000416
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000416.1, NP_000407.1
• RefSeq Size: 2059 bp
• RefSeq ORF: 1470 bp
• Locus ID: 3459
• UniProt ID: P15260
• Cytogenetics: 6q23.3
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity
• Gene Summary: This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes the longest isoform (1).