Stanniocalcin 2 (STC2) (NM_003714) Human Untagged Clone

SKU SC320177

STC2 (untagged)-Human stanniocalcin 2 (STC2)

Product Data

• Type: Human Untagged Clone
• Target Symbol: Stanniocalcin 2
• Synonyms: STC-2; STCRP
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_003714.2 CATCCCTGCCATTGCCGGGCACTCGCGGCGCTGCTAACGGCCTGGTCACATGCTCTCCGG; AGAGCTACGGGAGGGCGCTGGGTAACCTCTATCCGAGCCGCGGCCGCGAGGAGGAGGGAA; AAGGCGAGCAAAAAGGAAGAGTGGGAGGAGGAGGGGAAGCGGCGAAGGAGGAAGAGGAGG; AGGAGGAAGAGGGGAGCACAAAGGATCCAGGTCTCCCGACGGGAGGTTAATACCAAGAAC; CATGTGTGCCGAGCGGCTGGGCCAGTTCATGACCCTGGCTTTGGTGTTGGCCACCTTTGA; CCCGGCGCGGGGGACCGACGCCACCAACCCACCCGAGGGTCCCCAAGACAGGAGCTCCCA; GCAGAAAGGCCGCCTGTCCCTGCAGAATACAGCGGAGATCCAGCACTGTTTGGTCAACGC; TGGCGATGTGGGGTGTGGCGTGTTTGAATGTTTCGAGAACAACTCTTGTGAGATTCGGGG; CTTACATGGGATTTGCATGACTTTTCTGCACAACGCTGGAAAATTTGATGCCCAGGGCAA; GTCATTCATCAAAGACGCCTTGAAATGTAAGGCCCACGCTCTGCGGCACAGGTTCGGCTG; CATAAGCCGGAAGTGCCCGGCCATCAGGGAAATGGTGTCCCAGTTGCAGCGGGAATGCTA; CCTCAAGCACGACCTGTGCGCGGCTGCCCAGGAGAACACCCGGGTGATAGTGGAGATGAT; CCATTTCAAGGACTTGCTGCTGCACGAACCCTACGTGGACCTCGTGAACTTGCTGCTGAC; CTGTGGGGAGGAGGTGAAGGAGGCCATCACCCACAGCGTGCAGGTTCAGTGTGAGCAGAA; CTGGGGAAGCCTGTGCTCCATCTTGAGCTTCTGCACCTCGGCCATCCAGAAGCCTCCCAC; GGCGCCCCCCGAGCGCCAGCCCCAGGTGGACAGAACCAAGCTCTCCAGGGCCCACCACGG; GGAAGCAGGACATCACCTCCCAGAGCCCAGCAGTAGGGAGACTGGCCGAGGTGCCAAGGG; TGAGCGAGGTAGCAAGAGCCACCCAAACGCCCATGCCCGAGGCAGAGTCGGGGGCCTTGG; GGCTCAGGGACCTTCCGGAAGCAGCGAGTGGGAAGACGAACAGTCTGAGTATTCTGATAT; CCGGAGGTGAAATGAAAGGCCTGGCCACGAAATCTTTCCTCCACGCCGTCCATTTTCTTA; TCTATGGACATTCCAAAACATTTACCATTAGAGAGGGGGGATGTCACACGCAGGATTCTG; TGGGGACTGTGGACTTCATCGAGGTGTGTGTTCGCGGAACGGACAGGTGAGATGGAGACC; CCTGGGGCCGTGGGGTCTCAGGGGTGCCTGGTGAATTCTGCACTTACACGTACTCAAGGG; AGCGCGCCCGCGTTATCCTCGTACCTTTGTCTTCTTTCCATCTGTGGAGTCAGTGGGTGT; CGGCCGCTCTGTTGTGGGGGAGGTGAACCAGGGAGGGGCAGGGCAAGGCAGGGCCCCCAG; AGCTGGGCCACACAGTGGGTGCTGGGCCTCGCCCCGAAGCTTCTGGTGCAGCAGCCTCTG; GTGCTGTCTCCGCGGAAGTCAGGGCGGCTGGATTCCAGGACAGGAGTGAATGTAAAAATA; AATATCGCTTAGAATGCAGGAGAAGGGTGGAGAGGAGGCAGGGGCCGAGGGGGTGCTTGG; TGCCAAACTGAAATTCAGTTTCTTGTGTGGGGCCTTGCGGTTCAGAGCTCTTGGCGAGGG; TGGAGGGAGGAGTGTCATTTCTATGTGTAATTTCTGAGCCATTGTACTGTCTGGGCTGGG; GGGGACACTGTCCAAGGGAGTGGCCCCTATGAGTTTATATTTTAACCACTGCTTCAAATC; TCGATTTCACTTTTTTTATTTATCCAGTTATATCTACATATCTGTCATCTAAATAAATGG; CTTTCAAACAAAAAAAAAAAAAAAAAA
• Restriction Sites: Please inquire
• ACCN: NM_003714
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_003714.2, NP_003705.1
• RefSeq Size: 5361 bp
• RefSeq ORF: 909 bp
• Locus ID: 8614
• UniProt ID: O76061
• Cytogenetics: 5q35.2
• Domains: Stanniocalcin
• Protein Families: Druggable Genome, Secreted Protein
• Summary: This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. [provided by RefSeq, Jul 2008]