Pannexin 2 (PANX2) (NM_052839) Human Untagged Clone

SKU SC314276

PANX2 (untagged)-Human pannexin 2 (PANX2), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: Pannexin 2
• Synonyms: hPANX2; PX2
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >SC314276 representing NM_052839.; Blue=Insert sequence Red=Cloning site Green=Tag(s); ; GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG; GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC; ATGCACCACCTCCTGGAGCAGTCGGCGGACATGGCGACCGCGCTGCTGGCGGGAGAGAAGCTGCGGGAG; CTGATCCTGCCGGGCGCGCAGGACGACAAGGCGGGCGCGCTGGCCGCGCTGCTTCTGCAGCTGAAGCTG; GAGCTGCCGTTCGACCGGGTGGTCACCATCGGCACCGTGCTGGTGCCCATCCTGCTGGTCACCCTGGTC; TTCACCAAGAACTTCGCAGAGGAACCCATTTACTGTTACACCCCGCACAACTTCACGCGCGACCAGGCG; CTGTACGCCCGCGGCTACTGCTGGACGGAGCTGCGGGACGCGCTGCCCGGCGTGGACGCCAGCCTGTGG; CCGTCGCTGTTTGAGCACAAGTTCCTGCCCTACGCGCTGCTGGCCTTCGCCGCCATCATGTACGTGCCC; GCGCTGGGCTGGGAGTTCCTGGCCTCCACGCGCCTCACCTCCGAGCTCAACTTCCTGCTGCAGGAGATC; GACAACTGTTACCACCGGGCGGCCGAGGGCCGCGCGCCCAAGATCGAGAAGCAGATCCAGTCCAAGGGC; CCGGGCATCACGGAGCGCGAGAAGCGCGAGATCATCGAGAACGCGGAGAAGGAGAAGAGCCCGGAGCAG; AACCTGTTCGAGAAGTACCTGGAGCGCCGCGGCCGCAGCAACTTCCTGGCCAAGCTGTACCTGGCGCGG; CACGTGCTGATCCTGCTGCTGAGCGCCGTGCCCATCTCCTACCTGTGCACCTACTACGCCACGCAGAAG; CAGAACGAGTTCACCTGCGCGCTGGGCGCGTCCCCGGACGGGGCGGCAGGTGCGGGGCCCGCGGTGCGC; GTGAGCTGCAAGCTCCCGTCCGTGCAACTGCAGCGCATCATCGCGGGCGTGGACATCGTGCTGCTGTGC; GTCATGAACCTCATCATCCTCGTCAACCTCATCCACCTCTTCATCTTCCGCAAGAGCAACTTCATCTTC; GACAAGCTGCACAAGGTGGGCATCAAGACGCGCCGGCAGTGGCGCCGCTCGCAGTTCTGCGACATCAAC; ATCCTGGCCATGTTCTGCAACGAGAACCGCGACCACATCAAGTCGCTCAACCGGCTGGACTTCATCACC; AACGAGAGCGACCTCATGTACGACAACGTGGTCCGGCAGCTGCTGGCGGCGCTGGCGCAGTCCAACCAC; GACGCCACCCCCACGGTGCGCGACTCGGGGGTGCAGACCGTGGACCCCAGCGCCAACCCCGCCGAGCCC; GACGGCGCCGCCGAGCCGCCCGTGGTCAAGCGGCCGCGCAAGAAGATGAAGTGGATCCCCACCAGCAAC; CCGCTTCCGCAGCCCTTCAAGGAGCCGCTGGCCATCATGCGCGTGGAGAACAGCAAGGCGGAGAAGCCG; AAGCCCGCGCGCAGGAAGACGGCCACGGACACGCTGATCGCGCCGCTGCTGGACCGCTCCGCCCACCAC; TACAAGGGCGGAGGGGGCGACCCGGGCCCCGGCCCCGCCCCTGCCCCCGCCCCGCCGCCCGCCCCTGAC; AAGAAGCACGCGCGCCACTTCTCCCTGGACGTGCACCCCTACATCCTCGGCACCAAGAAGGCCAAGGCC; GAGGCGGTGCCCGCCGCCCTGCCCGCCTCCCGGAGCCAGGAGGGGGGCTTCCTGTCCCAGGCGGAGGAC; TGTGGGCTAGGCCTGGCCCCGGCGCCCATCAAAGATGCTCCGCTCCCCGAGAAGGAAATCCCGTACCCC; ACAGAGCCAGCCCGGGCAGGGCTTCCCTCGGGGGGCCCGTTCCACGTCCGCTCACCTCCCGCCGCCCCT; GCTGTGGCCCCTCTGACACCAGCCAGCCTGGGCAAGGCGGAGCCCCTCACCATCCTGAGCCGAAACGCC; ACACACCCGCTGCTGCACATCAACACGCTGTACGAGGCCCGGGAGGAGGAGGACGGGGGCCCCCGCCTG; CCGCAGGACGTGGGGGACCTCATCGCCATCCCTGCCCCACAGCAGATCCTCATCGCCACCTTCGACGAG; CCGAGAACGGTCGTGAGTACTGTGGAGTTTTGA; ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT; TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC;
• Restriction Sites: SgfI-MluI
• ACCN: NM_052839
• Insert Size: 2034 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_052839.3
• RefSeq Size: 3069 bp
• RefSeq ORF: 2034 bp
• Locus ID: 56666
• UniProt ID: Q96RD6
• Cytogenetics: 22q13.33
• Protein Families: Transmembrane
• MW: 74.4 kDa
• Summary: The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 1 are abundantly expressed in central nervous system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 1 may form cell type-specific gap junctions with distinct properties. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]; Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).