Neurokinin 1 Receptor (TACR1) (NM_015727) Human Untagged Clone

SKU SC304352

TACR1 (untagged)-Human tachykinin receptor 1 (TACR1), transcript variant short

Product Data

• Type: Human Untagged Clone
• Target Symbol: Neurokinin 1 Receptor
• Synonyms: NK1R; NKIR; SPR; TAC1R
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_015727 edited; AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAG; AGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAG; AGAGAGAGAGAGAGAGAGGCCCGCGAAACTGCAGGCGGCGGCAGCGGCAGCAAAAGAGAA; GGAAAAATCTCCAGCTGGATACGAAGCTCCAGAATCCTGGCCATAGGCTCAGAACTTTTA; CAGGTCGCGCTGCAATGGGCCCCCACTCCCTCCTAAGTCCTCACGCAGCACAGGGCTTTG; CCTTTCCCTGCGGAGGAAGGAGAAATAGGAGTTGCAGGCAGCAGCAGGTGCATAAATGCG; GGGGATCTCTTGCTTCCTAGAACTGTGACCGGTGGAATTTCTTTCCCTTTTTCAGTTTAC; CGCAAGAGAGATGCTGTCTCCAGACTTCTGAACTCAAACGTCTCCTGAAGCTTGAAAGTG; GAGGAATTCAGAGCCACCGCGGGCAGGCGGGCAGTGCATCCAGAAGCGTTTATATTCTGA; GCGCCAGTTCAGCTTTCAAAAAGAGTGCTGCCCAGAAAAAGCCTTCCACCCTCCTGTCTG; GCTTTAGAAGGACCCTGAGCCCCAGGCGCCAGCCACAGGACTCTGCTGCAGAGGGGGGTT; GTGTACAGATAGTAGGGCTTTACCGCCTAGCTTCGAAATGGATAACGTCCTCCCGGTGGA; CTCAGACCTCTCCCCAAACATCTCCACTAACACCTCGGAACCCAATCAGTTCGTGCAACC; AGCCTGGCAAATTGTCCTTTGGGCAGCTGCCTACACGGTCATTGTGGTGACCTCTGTGGT; GGGCAACGTGGTAGTGATGTGGATCATCTTAGCCCACAAAAGAATGAGGACAGTGACGAA; CTATTTTCTGGTGAACCTGGCCTTCGCGGAGGCCTCCATGGCTGCATTCAATACAGTGGT; GAACTTCACCTATGCTGTCCACAACGAATGGTACTACGGCCTGTTCTACTGCAAGTTCCA; CAACTTCTTTCCCATCGCCGCTGTCTTCGCCAGTATCTACTCCATGACGGCTGTGGCCTT; TGATAGGTACATGGCCATCATACATCCCCTCCAGCCCCGGCTGTCAGCCACAGCCACCAA; AGTGGTCATCTGTGTCATCTGGGTCCTGGCTCTCCTGCTGGCCTTCCCCCAGGGCTACTA; CTCAACCACAGAGACCATGCCCAGCAGAGTCGTGTGCATGATCGAATGGCCAGAGCATCC; GAACAAGATTTATGAGAAAGTGTACCACATCTGTGTGACTGTGCTGATCTACTTCCTCCC; CCTGCTGGTGATTGGCTATGCATACACCGTAGTGGGAATCACACTATGGGCCAGTGAGAT; CCCCGGGGACTCCTCTGACCGCTACCACGAGCAAGTCTCTGCCAAGCGCAAGGTGGTCAA; AATGATGATTGTCGTGGTGTGCACCTTCGCCATCTGCTGGCTGCCCTTCCACATCTTCTT; CCTCCTGCCCTACATCAACCCAGATCTCTACCTGAAGAAGTTTATCCAGCAGGTCTACCT; GGCCATCATGTGGCTGGCCATGAGCTCCACCATGTACAACCCCATCATCTACTGCTGCCT; CAATGACAGGTGA;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015727 unedited; GCTGCCCAGNAAAAAGCCTTCCACCCTCCTGTCTGGCTTTAGAAGGACCCTGAGCCCCAG; GCGCCAGCCACAGGACTCTGCTGCAGAGGGGGGTTGTGTACAGATAGTAGGGCTTTGCCG; CCTAGCTTCGAAATGGATAACGTCCTCCCGGTGGACTCAGACCTCTCCCCAAACATCTCC; ACTAACACCTCGGAACCCAATCAGTTCGTGCAACCAGCCTGGCAAATTGTCCTTTGGGCA; GCTGCCTACACGGTCATTGTGGTGACCTCTGTGGTGGGCAACGTGGTAGTGATGTGGATC; ATCTTAGCCCACAAAAGAATGAGGACAGTGACGAACTATTTTCTGGTGAACCTGGCCTTC; GCGGAGGCCTCCATGGCTGCATTCAATACAGTGGTGAACTTCACCTATGCTGTCCACAAC; GAATGGTACTACGGCCTGTTCTACTGCAAGTTCCACAACTTCTTTCCCATCGCCGCTGTC; TTCGCCAGTATCTACTCCATGACGGCTGTGGCCTTTGATAGGTACATGGCCATCATACAT; CCNCTCCAGCCCCGGCTGTCAGCCACAGCCACCAAAGTGGTCATCTGTGTCATCTGGGTC; CTGGCTCTCCTGCTGGCCTTCCCNCCAGGCTACTACTCAACCACAGAGACCATGCCCAGC; AGAGTCGTGTGCATGATCGAATGGCCAGAGCATCCGAACAAGATTTATGAGAAAGTGTAC; CACATCTGTGTGACTGTGCTGATCTACTTCCTTCCCCTGCTGGTGATTGGCTATGCATAC; ACGGTATTGGGAATCACACTATGGGCCAGTGAGATCCCGGGGGACTTCTCTGACCGGTAC; CACAG;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_015727 unedited; NGGCCCCCTTGGAATGGCAACTTCCAGGNCCAGNAAAGCACTGGGGNAGGGTCACAGGNA; TGCCACCCGGGNATTCTGTTCAGGNAAACAGCTATGACCGCGGCCGCAATCTCACCTGTC; ATTGAGGCAGCAGTAGATGATGGGGTTGTACATGGTGGAGCTCATGGCCAGCCACATGAT; GGCCAGGTAGACCTGCTGGATAAACTTCTTCAGGTAGAGATCTGGGTTGATGTAGGGCAG; GAGGAAGAAGATGTGGAAGGGCAGCCAGCAGATGGCGAAGGTGCACACCACGACAATCAT; CATTTTGACCACCTTGCGCTTGGCAGAGACTTGCTCGTGGTAGCGGTCAGAGGAGTCCCC; GGGGATCTCACTGGCCCATAGTGTGATTCCCACTACGGTGTATGCATAGCCAATCACCAG; CAGGGGGAGGAAGTAGATCAGCACAGTCACACAGATGTGGTACACTTTCTCATAAATCTT; GTTCGGATGCTCTGGCCATTCGATCATGCACACGACTCTGCTGGGCATGGTCTCTGTGGT; TGAGTAGTAGCCCTGNGGGAAGGCCAGCANGAGAGCCAGGACCCAGATGACACAGATGAC; CACTTTGGTGGCTGTGGCTGACAGCCGGNGCTGGAGGGGATGTATGATGGCCATGTACCT; ATCANAGGCACAGCCGTCATGGAGTAGATACTGGCGAAAGACAGCGCGATGGGGAAAGAA; AGTGTGAAACTGCAGTAGAACAGGCCGTAGTACCATTNCGTGNNTGACAGCATAGTGAAG; TTCACCACTGTATTGAATGCAGCCATGGAGGCCTNCGCGAAGGCCAGGTCACCANAAAAT; AGTNCGTCACTGTCCTCATTCTTTTGGGGNCTAAGATGATCCCCATCACCTACACGTTNG; CCACCACAGAA;
• Restriction Sites: Please inquire
• ACCN: NM_015727
• Insert Size: 1600 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_015727.1.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_015727.1, NP_056542.1
• RefSeq Size: 1268 bp
• RefSeq ORF: 936 bp
• Locus ID: 6869
• UniProt ID: P25103
• Cytogenetics: 2p12
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction
• Summary: This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq, Sep 2008]; Transcript Variant: This variant (short) uses a different splice site in the 3' coding region, compared to variant long. The resulting protein (isoform short) has a shorter and distinct C-terminus when compared to the long isoform. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.