MRC2 (NM_006039) Human Untagged Clone

CAT#: SC303722

MRC2 (untagged)-Human mannose receptor, C type 2 (MRC2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MRC2
• Synonyms: CD280; CLEC13E; ENDO180; UPARAP
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >SC303722 representing NM_006039.
  Blue=Insert sequence Red=Cloning site Green=Tag(s)
  
  GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG
  GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC
  ATGGGGCCCGGCCGGCCGGCCCCCGCGCCCTGGCCTCGTCACCTGCTGCGCTGCGTCCTGCTCCTCGGG
  TGCCTGCACCTCGGCCGTCCCGGCGCCCCTGGGGACGCCGCCCTCCCGGAACCCAACGTCTTCCTCATC
  TTCAGCCATGGACTGCAGGGCTGCCTGGAGGCCCAGGGCGGGCAGGTCAGAGTCACCCCGGCTTGCAAT
  ACCAGCCTCCCTGCCCAGCGCTGGAAGTGGGTCTCCCGAAACCGGCTATTCAACCTGGGTACCATGCAG
  TGCCTGGGCACAGGCTGGCCAGGCACCAACACCACGGCCTCCCTGGGCATGTATGAGTGTGACCGGGAA
  GCACTGAATCTTCGCTGGCATTGTCGTACACTGGGTGACCAGCTGTCCTTGCTCCTGGGGGCCCGCACC
  AGCAACATATCCAAGCCTGGCACCCTTGAGCGTGGTGACCAGACCCGCAGTGGCCAGTGGCGCATCTAC
  GGCAGCGAGGAGGACCTATGTGCTCTGCCCTACCACGAGGTCTACACCATCCAGGGAAACTCCCACGGA
  AAGCCGTGCACCATCCCCTTCAAATATGACAACCAGTGGTTCCACGGCTGCACCAGCACGGGCCGCGAG
  GATGGTCACCTGTGGTGTGCCACCACCCAGGACTACGGCAAAGACGAGCGCTGGGGCTTCTGCCCCATC
  AAGAGTAACGACTGCGAGACCTTCTGGGACAAGGACCAGCTGACTGACAGCTGCTACCAGTTTAACTTC
  CAGTCCACGCTGTCGTGGAGGGAGGCCTGGGCCAGCTGCGAGCAGCAGGGTGCGGATCTGCTGAGCATC
  ACGGAGATCCACGAGCAGACCTACATCAACGGCCTCCTCACTGGGTACAGCTCCACCCTGTGGATCGGC
  TTGAATGACTTGGACACGAGCGGAGGCTGGCAGTGGTCGGACAACTCGCCCCTCAAGTACCTCAACTGG
  GAGAGTGACCAGCCGGACAACCCCAGTGAGGAGAACTGTGGAGTGATCCGCACTGAGTCCTCGGGCGGC
  TGGCAGAACCGTGACTGCAGCATCGCGCTGCCCTATGTGTGCAAGAAGAAGCCCAACGCCACGGCCGAG
  CCCACCCCTCCAGACAGGTGGGCCAATGTGAAGGTGGAGTGCGAGCCGAGCTGGCAGCCCTTCCAGGGC
  CACTGCTACCGCCTGCAGGCCGAGAAGCGCAGCTGGCAGGAGTCCAAGAAGGCATGTCTACGGGGCGGT
  GGCGACCTGGTCAGCATCCACAGCATGGCGGAGCTGGAATTCATCACCAAGCAGATCAAGCAAGAGGTG
  GAGGAGCTGTGGATCGGCCTCAACGATTTGAAACTGCAGATGAATTTTGAGTGGTCTGACGGGAGCCTT
  GTGAGCTTCACCCACTGGCACCCCTTTGAGCCCAACAACTTCCGGGACAGTCTGGAGGACTGTGTCACC
  ATCTGGGGCCCGGAAGGCCGCTGGAACGACAGTCCCTGTAACCAGTCCTTGCCATCCATCTGCAAGAAG
  GCAGGCCAGCTGAGCCAGGGGGCCGCCGAGGAGGACCATGGCTGCCGGAAGGGTTGGACGTGGCACAGC
  CCATCCTGCTACTGGCTGGGAGAAGACCAAGTGACCTACAGTGAGGCCCGGCGCCTGTGCACTGACCAT
  GGCTCTCAGCTGGTCACCATCACCAACAGGTTCGAGCAGGCCTTCGTCAGCAGCCTCATCTACAACTGG
  GAGGGCGAGTACTTCTGGACGGCCCTGCAGGACCTCAACAGCACCGGCTCCTTCTTCTGGCTCAGTGGG
  GATGAAGTCATGTACACCCACTGGAACCGGGACCAGCCCGGGTACAGCCGTGGGGGCTGCGTGGCGCTG
  GCCACTGGCAGCGCCATGGGGCTGTGGGAGGTGAAGAACTGTACCTCGTTCCGGGCCCGCTACATCTGC
  CGGCAGAGCCTGGGCACTCCAGTGACGCCGGAGCTGCCGGGGCCAGATCCCACGCCCAGCCTCACTGGC
  TCCTGTCCCCAGGGCTGGGCCTCGGACACCAAACTCCGGTATTGCTATAAGGTGTTCAGCTCAGAGCGG
  CTGCAGGACAAGAAGAGCTGGGTCCAGGCCCAGGGGGCCTGCCAGGAGCTGGGGGCCCAGCTGCTGAGC
  CTGGCCAGCTACGAGGAGGAGCACTTTGTGGCCAACATGCTCAACAAGATCTTCGGTGAATCAGAACCC
  GAGATCCACGAGCAGCACTGGTTCTGGATCGGCCTGAACCGTCGGGATCCCAGAGGGGGTCAGAGTTGG
  CGCTGGAGCGACGGCGTAGGGTTCTCTTACCACAATTTCGACCGGAGCCGGCACGACGACGACGACATC
  CGAGGCTGTGCGGTGCTGGACCTGGCCTCCCTGCAGTGGGTGGCCATGCAGTGCGACACACAGCTGGAC
  TGGATCTGCAAGATCCCCAGAGGTACGGACGTGCGGGAGCCCGACGACAGCCCTCAAGGCCGACGGGAA
  TGGCTGCGCTTCCAGGAGGCCGAGTACAAGTTCTTTGAGCACCACTCCACGTGGGCGCAGGCGCAGCGC
  ATCTGCACGTGGTTCCAGGCCGAGCTGACCTCGGTGCACAGCCAGGCGGAGCTAGACTTCCTGAGCCAC
  AACTTGCAGAAGTTCTCCCGGGCCCAGGAGCAGCACTGGTGGATCGGCCTGCACACCTCTGAGAGCGAT
  GGGCGCTTCAGATGGACAGATGGTTCCATTATAAACTTCATCTCCTGGGCACCAGGCAAACCTCGGCCT
  GTCGGCAAGGACAAGAAGTGCGTGTACATGACAGCCAGCCGAGAGGACTGGGGGGACCAGAGGTGCCTG
  ACAGCCTTGCCCTACATCTGCAAGCGCAGCAACGTCACCAAAGAAACGCAGCCCCCAGACCTGCCAACT
  ACAGCCCTGGGGGGCTGCCCCTCTGACTGGATCCAGTTCCTCAACAAGTGTTTTCAGGTCCAGGGCCAG
  GAACCCCAGAGCCGGGTGAAGTGGTCAGAGGCACAGTTCTCCTGTGAACAGCAAGAGGCCCAGCTGGTC
  ACCATCACAAACCCCTTAGAGCAAGCATTCATCACAGCCAGCCTGCCCAATGTGACCTTTGACCTTTGG
  ATTGGCCTCCATGCCTCGCAGAGGGACTTCCAGTGGGTGGAGCAGGAGCCTTTGATGTATGCCAACTGG
  GCACCTGGGGAGCCCTCTGGCCCTAGCCCTGCTCCCAGTGGCAACAAACCGACCAGCTGTGCAGTGGTC
  CTGCACAGCCCCTCAGCCCACTTCACTGGCCGCTGGGACGATCGGAGCTGCACGGAGGAGACCCATGGC
  TTCATCTGCCAGAAGGGCACGGACCCCTCCCTGAGCCCGTCCCCAGCAGCGCTGCCCCCCGCCCCGGGC
  ACTGAGCTCTCCTACCTCAACGGCACCTTCCGGCTGCTTCAGAAGCCGCTGCGCTGGCACGATGCCCTC
  CTGCTGTGTGAGAGCCGCAATGCCAGCCTGGCCTACGTGCCCGACCCCTACACCCAGGCCTTCCTCACG
  CAGGCTGCCCGAGGGCTGCGCACGCCGCTCTGGATTGGGCTGGCTGGCGAGGAGGGCTCTCGGCGGTAC
  TCCTGGGTCTCAGAGGAGCCGCTGAACTACGTGGGCTGGCAGGACGGGGAGCCGCAGCAGCCGGGGGGC
  TGTACCTACGTAGATGTGGACGGGGCCTGGCGCACCACCAGCTGTGACACCAAGCTGCAGGGGGCTGTG
  TGTGGGGTTAGCAGTGGGCCCCCTCCTCCCCGAAGAATAAGCTACCATGGCAGCTGTCCCCAGGGACTG
  GCAGACTCCGCGTGGATTCCCTTCCGGGAGCACTGCTATTCTTTCCACATGGAGCTGCTGCTGGGCCAC
  AAGGAGGCGCGACAGCGCTGCCAGAGAGCGGGTGGGGCCGTCCTGTCTATCCTGGATGAGATGGAGAAT
  GTGTTTGTCTGGGAGCACCTGCAGAGCTATGAGGGCCAGAGTCGGGGCGCCTGGCTGGGCATGAACTTC
  AACCCCAAAGGAGGCACTCTGGTCTGGCAGGACAACACAGCTGTGAACTACTCCAACTGGGGGCCCCCG
  GGCTTGGGCCCCAGCATGCTGAGCCACAACAGCTGCTACTGGATTCAGAGCAACAGCGGGCTATGGCGC
  CCCGGCGCTTGCACCAACATCACCATGGGTGTCGTCTGCAAGCTTCCTCGTGCTGAGCAGAGCAGCTTC
  TCCCCATCAGCGCTTCCAGAGAACCCAGCGGCCCTGGTGGTGGTGCTGATGGCGGTGCTGCTGCTCCTG
  GCCTTGCTGACCGCAGCCCTCATCCTTTACCGGAGGCGCCAGAGCATCGAGCGCGGGGCCTTTGAGGGT
  GCCCGCTACAGCCGCAGCAGCTCCAGCCCCACCGAGGCCACTGAGAAGAACATCCTGGTGTCAGACATG
  GAAATGAATGAGCAACAAGAATAG
  ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT
  TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC
  
• Restriction Sites: SgfI-MluI
• ACCN: NM_006039
• Insert Size: 4440 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006039.4
• RefSeq Size: 6004 bp
• RefSeq ORF: 4440 bp
• Locus ID: 9902
• UniProt ID: Q9UBG0
• Cytogenetics: 17q23.2
• Protein Families: Druggable Genome, Transmembrane
• MW: 166.7 kDa
• Gene Summary: This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease. [provided by RefSeq, Feb 2012]