Mannose Receptor (MRC1) (NM_002438) Human Untagged Clone

SKU SC303200

MRC1 (untagged)-Human mannose receptor, C type 1 (MRC1)

Product Data

• Type: Human Untagged Clone
• Target Symbol: Mannose Receptor
• Synonyms: bA541I19.1; CD206; CLEC13D; CLEC13DL; hMR; MMR; MRC1L1
• Vector: pCMV6-Entry
• E. coli Selection: Kanamycin (25 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_002438 edited; GCGATCGCCATGAGGCTACCCCTGCTCCTGGTTTTTGCCTCTGTCATTCCGGGTGCTGTT; CTCCTACTGGACACCAGGCAATTTTTAATCTATAATGAAGATCACAAGCGCTGCGTGGAT; GCAGTGAGTCCCAGTGCCGTCCAAACCGCAGCTTGCAACCAGGATGCCGAATCACAGAAA; TTCCGATGGGTGTCCGAATCTCAGATTATGAGTGTTGCATTTAAATTATGCCTGGGAGTG; CCATCAAAAACGGACTGGGTTGCTATCACTCTCTATGCCTGTGACTCAAAAAGTGAATTT; CAGAAATGGGAGTGCAAAAATGACACACTTTTGGGGATCAAAGGAGAAGATTTATTTTTT; AACTACGGCAACAGACAAGAAAAGAATATTATGCTCTACAAGGGATCGGGTTTATGGAGC; AGGTGGAAGATCTATGGAACCACAGACAATCTGTGCTCCAGAGGTTATGAAGCCATGTAT; ACGCTACTAGGCAATGCCAATGGAGCAACCTGTGCATTCCCGTTCAAGTTTGAAAACAAG; TGGTACGCAGATTGCACGAGTGCTGGGCGGTCGGATGGATGGCTCTGGTGCGGAACCACT; ACTGACTATGACACAGACAAGCTATTTGGATATTGTCCATTGAAATTTGAGGGCAGTGAA; AGCTTATGGAATAAAGACCCGCTGACCAGCGTTTCCTACCAGATAAACTCCAAATCCGCT; TTAACGTGGCACCAGGCGAGGAAAAGCTGCCAACAACAGAACGCTGAGCTCCTGAGCATC; ACAGAGATTCATGAGCAAACATACCTGACAGGATTAACCAGTTCCTTGACCTCAGGACTC; TGGATTGGACTTAACAGTCTGAGCTTCAACAGCGGTTGGCAGTGGAGTGACCGCAGTCCT; TTCCGATATTTGAACTGGTTACCAGGAAGTCCATCAGCTGAACCTGGAAAAAGCTGTGTG; TCACTAAATCCTGGAAAAAATGCTAAATGGGAAAATCTGGAATGTGTTCAGAAACTGGGC; TATATTTGCAAAAAGGGCAACACCACTTTAAATTCTTTTGTTATTCCCTCAGAAAGTGAT; GTGCCTACTCACTGTCCTAGTCAGTGGTGGCCGTATGCCGGTCACTGTTACAAGATTCAC; AGAGATGAGAAAAAAATCCAGAGGGATGCTCTGACCACCTGCAGGAAGGAAGGCGGTGAC; CTCACAAGTATCCACACCATCGAGGAATTGGACTTTATTATCTCCCAGCTAGGATATGAG; CCAAATGACGAATTGTGGATCGGCTTAAATGACATTAAGATTCAAATGTACTTTGAGTGG; AGTGATGGGACCCCTGTAACGTTTACCAAATGGCTTCGTGGAGAACCAAGCCATGAAAAC; AACAGACAGGAGGATTGTGTGGTGATGAAAGGCAAGGATGGGTACTGGGCAGATCGGGGC; TGTGAGTGGCCTCTTGGCTACATCTGCAAGATGAAATCACGAAGCCAAGGTCCAGAAATA; GTGGAAGTCGAAAAAGGCTGCAGGAAAGGCTGGAAAAAACATCACTTTTACTGCTATATG; ATTGGACATACGCTTTCAACATTTGCAGAAGCAAACCAAACCTGTAATAATGAGAATGCT; TATTTAACAACTATTGAAGACAGATATGAACAAGCCTTCCTGACTAGTTTCGTTGGCTTA; AGGCCTGAAAAATATTTCTGGACAGGACTTTCAGATATACAAACCAAAGGGACTTTTCAG; TGGACCATCGAGGAAGAGGTTCGGTTCACCCACTGGAATTCAGATATGCCAGGGCGAAAG; CCAGGGTGTGTTGCCATGAGAACCGGGATTGCAGGGGGCTTATGGGATGTTTTGAAATGT; GATGAAAAGGCAAAATTTGTGTGCAAGCACTGGGCAGAAGGAGTAACCCACCCACCGAAG; CCCACGACGACTCCCGAACCCAAATGTCCGGAGGATTGGGGCGCCAGCAGTAGAACAAGC; TTGTGTTTCAAGCTGTATGCAAAAGGAAAACATGAGAAGAAAACGTGGTTTGAATCTCGA; GATTTTTGTCGAGCTCTGGGTGGAGACTTAGCTAGCATCAATAACAAAGAGGAACAGCAA; ACAATATGGCGATTAATAACAGCTAGTGGAAGCTACCACAAACTGTTTTGGTTGGGATTG; ACATATGGAAGCCCTTCAGAAGGTTTTACTTGGAGTGATGGTTCTCCTGTTTCATATGAA; AACTGGGCTTATGGAGAACCTAATAATTATCAAAATGTTGAATACTGTGGTGAGCTGAAA; GGTGACCCTACTATGTCTTGGAATGATATTAATTGTGAACACCTTAACAACTGGATTTGC; CAGATACAAAAAGGACAAACACCAAAACCTGAGCCAACACCAGCTCCTCAAGACAATCCA; CCAGTTACTGAAGATGGGTGGGTTATTTACAAAGACTACCAGTATTATTTCAGCAAAGAG; AAGGAAACCATGGACAATGCGCGAGCGTTTTGCAAGAGGAATTTTGGTGATCTTGTTTCT; ATTCAAAGTGAAAGTGAAAAGAAGTTTCTATGGAAATATGTAAACAGAAATGATGCACAG; TCTGCATATTTTATTGGTTTATTGATCAGCTTGGATAAAAAGTTTGCTTGGATGGATGGA; AGCAAAGTGGATTACGTGTCTTGGGCCACAGGTGAACCCAATTTTGCAAATGAAGATGAA; AACTGTGTGACCATGTATTCAAATTCAGGGTTTTGGAATGACATTAACTGTGGCTATCCA; AACGCCTTCATTTGCCAGCGACATAACAGTAGTATCAATGCTACCACAGTTATGCCTACC; ATGCCCTCGGTCCCATCAGGGTGCAAGGAAGGTTGGAATTTCTACAGCAACAAGTGTTTC; AAAATCTTTGGATTTATGGAAGAAGAAAGAAAAAATTGGCAAGAGGCACGAAAAGCTTGT; ATAGGCTTTGGAGGGAATCTGGTCTCCATACAAAATGAAAAAGAGCAAGCATTTCTTACC; TATCACATGAAGGACTCCACTTTCAGTGCCTGGACTGGGCTGAATGATGTCAATTCAGAA; CACACGTTCCTTTGGACGGATGGACGAGGAGTCCATTACACAAACTGGGGGAAAGGTTAC; CCTGGTGGAAGAAGAAGCAGTCTTTCTTATGAAGATGCTGACTGTGTTGTTATTATTGGA; GGTGCATCAAATGAAGCAGGAAAATGGATGGATGATACCTGCGACAGTAAACGAGGCTAC; ATATGCCAGACACGATCCGACCCTTCCTTGACTAATCCTCCAGCAACGATTCAAACAGAT; GGCTTTGTTAAATATGGCAAAAGCAGCTATTCACTCATGAGACAAAAATTTCAATGGCAT; GAAGCGGAGACATACTGCAAGCTTCACAATTCCCTTATAGCCAGCATTCTGGATCCCTAC; AGTAATGCATTTGCGTGGCTGCAGATGGAAACATCTAATGAACGTGTGTGGATTGCCCTG; AACAGTAACTTGACTGATAATCAATACACTTGGACTGATAAGTGGAGGGTGAGGTACACT; AACTGGGCTGCTGATGAGCCCAAATTGAAATCAGCATGTGTTTATCTGGATCTTGATGGC; TACTGGAAGACAGCACATTGCAATGAAAGTTTTTACTTTCTCTGTAAAAGATCAGATGAA; ATCCCTGCTACTGAACCCCCACAACTGCCTGGCAGATGCCCGGAGTCAGATCACACAGCA; TGGATTCCTTTCCATGGTCACTGTTACTATATTGAGTCCTCATATACAAGAAACTGGGGC; CAAGCTTCTCTGGAATGTCTTCGAATGGGTTCCTCTCTGGTTTCCATTGAAAGTGCTGCA; GAATCCAGTTTTCTGTCATATCGGGTTGAGCCACTTAAAAGTAAAACCAATTTTTGGATA; GGATTGTTCAGAAATGTTGAAGGGACGTGGCTGTGGATAAATAACAGTCCGGTCTCCTTT; GTCAACTGGAACACAGGAGATCCCTCTGGTGAACGGAATGATTGTGTAGCTTTACATGCG; TCTTCTGGGTTTTGGAGTAATATTCACTGTTCTTCCTACAAAGGATATATTTGTAAAAGA; CCAAAAATTATTGATGCTAAACCTACTCATGAATTACTTACAACAAAAGCTGACACAAGG; AAGATGGACCCTTCTAAACCGTCTTCCAACGTGGCCGGAGTAGTCATCATTGTGATCCTC; CTGATTTTAACGGGTGCTGGCCTTGCCGCCTATTTCTTTTATAAGAAAAGACGTGTGCAC; CTACCTCAAGAGGGCGCCTTTGAAAACACTCTGTATTTTAACAGTCAGTCAAGCCCAGGA; ACTAGTGATATGAAAGATCTCGTGGGCAATATTGAACAGAATGAACACTCGGTCATCTAG; TACCTCAATGCGATTCTGAGATATTTGAATTTCATAAAATTGTAACTGAAATTTAAAATT; TTTAGTTCAATGTGATTGTTTTCTTTAAAATGAGTACTGAATTGTACTGGTCTGTCCTTT; TTTCCTTTGCCTAATTGAAGAAATAATTGCTTGTTTTCTAGCCTGGCAAGATATTTTCAT; AAAAGAGGGATAACAATGCTGATTACTACCTTTTAAAATATTTTAGATAAATGCACAGCA; CCACAGCACCACATCTAAGCATTAGTGATGGGTAGCTGATGTCAGCTTCATGTGGATTTT; AAGCACTCTAGAAACAATGAAGCTTCTTGGCATATTTTAAGGAGCTCCCAAAATGTGTTA; CCTATTAAATTGTAACTCAGCAAGTAGAAGACCATTTGAAAAGTCAGGTACAAATATCCT; CAAGTGGCATAAAAATGTAGTCAGTTTTCTCTTTTACCAGTTTTTATTTCCACTCCAATT; ATTTAGAACTTTATTTGTACATGTGCAGAAGAATAAGGCAGCTGAGAATCTTGTTTCCCC; CAAGAGAGTTTTACAGGCTGAGTGTTGCAAATGTGTTCTTTGTCCTGTTATATGTATATC; AGGAATACAAGGATGTGAAATAAAACTGTAAATTTGCATAACTGGATGTACTTAGATAAT; GTGAAATAAACATTAAAGACAAGGTCTATTTTTAATA;
• Restriction Sites: Please inquire
• ACCN: NM_002438
• Insert Size: 4371 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to the protein associated with NM_002438.1.
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_002438.1, NP_002429.1
• RefSeq Size: 5185 bp
• RefSeq ORF: 4371 bp
• Locus ID: 4360
• UniProt ID: P22897
• Cytogenetics: 10p12.33
• Protein Families: Druggable Genome, Transmembrane
• Summary: The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]