ST2 (IL1RL1) (NM_003856) Human Untagged Clone

SKU SC127817

IL1RL1 (untagged)-Human interleukin 1 receptor-like 1 (IL1RL1), transcript variant 2

Product Data

• Type: Human Untagged Clone
• Target Symbol: ST2
• Synonyms: DER4; FIT-1; IL33R; ST2; ST2L; ST2V; T1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC127817 sequence for NM_003856 edited (data generated by NextGen Sequencing); ATGGGGTTTTGGATCTTAGCAATTCTCACAATTCTCATGTATTCCACAGCAGCAAAGTTT; AGTAAACAATCATGGGGCCTGGAAAATGAGGCTTTAATTGTAAGATGTCCTAGACAAGGA; AAACCTAGTTACACCGTGGATTGGTATTACTCACAAACAAACAAAAGTATTCCCACTCAG; GAAAGAAATCGTGTGTTTGCCTCAGGCCAACTTCTGAAGTTTCTACCAGCTGCAGTTGCT; GATTCTGGTATTTATACCTGTATTGTCAGAAGTCCCACATTCAATAGGACTGGATATGCG; AATGTCACCATATATAAAAAACAATCAGATTGCAATGTTCCAGATTATTTGATGTATTCA; ACAGTATCTGGATCAGAAAAAAATTCCAAAATTTATTGTCCTACCATTGACCTCTACAAC; TGGACAGCACCTCTTGAGTGGTTTAAGAATTGTCAGGCTCTTCAAGGATCAAGGTACAGG; GCGCACAAGTCATTTTTGGTCATTGATAATGTGATGACTGAGGACGCAGGTGATTACACC; TGTAAATTTATACACAATGAAAATGGAGCCAATTATAGTGTGACGGCGACCAGGTCCTTC; ACGGTCAAGGATGAGCAAGGCTTTTCTCTGTTTCCAGTAATCGGAGCCCCTGCACAAAAT; GAAATAAAGGAAGTGGAAATTGGAAAAAACGCAAACCTAACTTGCTCTGCTTGTTTTGGA; AAAGGCACTCAGTTCTTGGCTGCCGTCCTGTGGCAGCTTAATGGAACAAAAATTACAGAC; TTTGGTGAACCAAGAATTCAACAAGAGGAAGGGCAAAATCAAAGTTTCAGCAATGGGCTG; GCTTGTCTAGACATGGTTTTAAGAATAGCTGACGTGAAGGAAGAGGATTTATTGCTGCAG; TACGACTGTCTGGCCCTGAATTTGCATGGCTTGAGAAGGCACACCGTAAGACTAAGTAGG; AAAAATCCAAGTAAGGAGTGTTTCTGA; ; Clone variation with respect to NM_003856.2;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003856 unedited; CGGTCACCATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACCAGCAAAAACTG; GAAACTATTCTTAGCTCCGTCACTGACTCCAAGTTCATCCCCTCTGTCTTTCAGTTTGGT; TGAGATATAGGCTACTCTTCCCAACTCAGTCTTGAAGAGTATCACCAACTGCCTCATGTG; TGGTGACCTTCACTGTCGTATGCCAGTGACTCATCTGGAGTAATCTCAACAACGAGTTAC; CAATACTTGCTCTTGATTGATAAACAGAATGGGGTTTTGGATCTTAGCAATTCTCACAAT; TCTCATGTATTCCACAGCAGCAAAGTTTAGTAAACAATCATGGGGCCTGGAAAATGAGGC; TTTAATTGTAAGATGTCCTAGACAAGGAAAACCTAGTTACACCGTGGATTGGTATTACTC; ACAAACAAACAAAAGTATTCCCACTCAGGAAAGAAATCGTGTGTTTGCCTCAGGCCAACT; TCTGAAGTTTCTACCAGCTGCAGTTGCTGATTCTGGTATTTATACCTGTATTGTCAGAAG; TCCCACATTCAATAGGACTGGATATGCGAATGTCACCATATATAAAAAACAATCAGATTG; CAATGTTCCAGATTATTTGATGTATTCAACAGTATCTGGATCAGAAAAAAATTCCAAAAT; TTATTGTCCTACCATTGACCTCTACAACTGGACAGCACCTCTTGAGTGGTTTAAGAATTG; TCAGGCTCTTCAGGATCAAGGTACAGGGCGCACAAGTCATTTTTGGTCATTGATAATGTG; ATGACTGAGGACGCANGTGATTACACCTGNTAATTATACACCATGAAATGGAGCANTNAT; AGTGTGACGGCGACCAGTCCTTCACGTCAGGATGAGCAAGCTTTTCTCTGTTTCCAGTAT; CGGAGCCCTGCCAAATGNATAAAGGNAGTGAAAATGGAAAAACCAACCTACTGCTCTN;
• Restriction Sites: NotI-NotI
• ACCN: NM_003856
• Insert Size: 2650 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_003856.2, NP_003847.2
• RefSeq Size: 2542 bp
• RefSeq ORF: 987 bp
• Locus ID: 9173
• UniProt ID: Q01638
• Cytogenetics: 2q12.1
• Protein Families: Druggable Genome, Secreted Protein, Transmembrane
• Summary: The protein encoded by this gene is a member of the interleukin 1 receptor family. Studies of the similar gene in mouse suggested that this receptor can be induced by proinflammatory stimuli, and may be involved in the function of helper T cells. This gene, interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2) and interleukin 1 receptor-like 2 (IL1RL2) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]; Transcript Variant: This variant (2) has an alternate 5' UTR exon and lacks several 3' terminal exons, and its transcription extends past a splice site that is used in variant 1, resulting in a novel 3' coding region and 3' UTR, compared to variant 1. It encodes isoform 2 which is shorter and has a distinct C-terminus, compared to isoform 1.