ZDHHC16 (NM_198045) Human Untagged Clone

SKU SC126361

ZDHHC16 (untagged)-Human zinc finger, DHHC-type containing 16 (ZDHHC16), transcript variant 4

Product Data

• Type: Human Untagged Clone
• Target Symbol: ZDHHC16
• Synonyms: APH2; DHHC-16
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_198045 edited; GCTGCCTGGCGCTGCGGGCGGCGGGCCATGGTGGTTTGGATTGAGCCGGGCCCGGCCGGG; GCGCCGAGTCGGAGGGGGTGGCAGTGAGCGGCGGCAGAGGCTACGGGGCTCGGTTTGGCT; GACTGGGGAGTCGGCAGGCGGCAGGAACCATGCGAGGCCAGCGGAGCCTGCTGCTGGGCC; CGGCCCGCCTCTGCCTCCGCCTCCTTCTGCTGCTGGGTTACAGGCGCCGCTGTCCACCTC; TACTCCGGGGTCTAGTACAGCGCTGGCGCTACGGCAAGGTCTGCCTGCGCTCCCTGCTCT; ACAACTCCTTTGGGGGCAGTGACACCGCTGTTGATGCTGCCTTTGAGCCTGTCTACTGGC; TGGTAGACAACGTGATCCGCTGGTTTGGAGTGGGCAGGAATGATATCGCCACCGTCTCCA; TCTGTAAGAAGTGCATTTACCCCAAGCCAGCCCGAACACACCACTGCAGCATCTGCAACA; GGTGTGTGCTGAAGATGGATCACCACTGCCCCTGGCTAAACAATTGTGTGGGCCACTATA; ACCATCGGTACTTCTTCTCTTTCTGCTTTTTCATGACTCTGGGCTGTGTCTACTGCAGCT; ATGGAAGTTGGGACCTTTTCCGGGAGGCTTATGCTGCCATTGAGACTTATCACCAGACCC; CACCACCCACCTTCTCCTTTCGAGAAAGGATGACTCACAAGAGTCTTGTCTACCTCTGGT; TCCTGTGCAGTTCTGTGGCACTTGCCCTGGGTGCCCTAACTGTATGGCATGCTGTTCTCA; TCAGTCGAGGTGAGACTAGCATCGAAAGGCACATCAACAAGAAGGAGAGACGTCGGCTAC; AGGCCAAGGGCAGAGTATTTAGGAATCCTTACAACTACGGCTGCTTGGACAACTGGAAGG; TATTCCTGGGTGTGGATACAGGAAGGCACTGGCTTACTCGGGTGCTCTTACCTTCTAGTC; ACTTGCCCCATGGGAATGGAATGAGCTGGGAGCCCCCTCCCTGGGTGACTGCTCACTCAG; CCTCTGTGATGGCAGTGTGAGCTGGACTGTGTCAGCCACGACTCGAGCACTCATTCTGCT; CCCTATGTTATTTCAAGGGCCTCCAAGGGCAGCTTTTCTCAGAATCCTTGATCAAAAAGA; GCCAGTGGGCCTGCCTTAGGGTACCATGCAGGACAATTCAAGGACCAGCCTTTTTACCAC; TGCAGAAGAAAGACACAATGTGGAGAAATCTTAGGACTGACATCCCTTTACTCAGGCAAA; CAGAAGTTCCAACCCCAGACTAGGGGTCAGGCAGCTAGCTACCTACCTTGCCCAGTGCTG; ACCCGGACCTCCTCCAGGATACAGCACTGGAGTTGGCCACCACCTCTTCTACTTGCTGTC; TGAAAAAACACCTGACTAGTACAGCTGAGATCTTGGCTTCTCAACAGGGCAAAGATACCA; GGCCTGCTGCTGAGGTCACTGCCACTTCTCACATGCTGCTTAAGGGAGCACAAATAAAGG; TATTCGATTTTTAAAGATAAAAAAAAAAAAAAAAAA;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_198045 unedited; NGGCCGTCAGATTTTGTATACGACTCATATAGGGCGGCCGCGAATTCGCACGAGGGCTGC; CTGGCGCTGCGGGCGGCGGGCCATGGTGGTTTGGATTGAGCCGGGCCCGGCCGGGGCGCC; GAGTCGGAGGGGGTGGCAGTGAGCGGCGGCAGAGGCTACGGGGCTCGGTTTGGCTGACTG; GGGAGTCGGCAGGCGGCAGGAACCATGCGAGGCCAGCGGAGCCTGCTGCTGGGCCCGGCC; CGCCTCTGCCTCCGCCTCCTTCTGCTGCTGGGTTACAGGCGCCGCTGTCCACCTCTACTC; CGGGGTCTAGTACAGCGCTGGCGCTACGGCAAGGTCTGCCTGCGCTCCCTGCTCTACAAC; TCCTTTGGGGGCAGTGACACCGCTGTTGATGCTGCCTTTGAGCCTGTCTACTGGCTGGTA; GACAACGTGATCCGCTGGTTTGGAGTGGGCAGGAATGATATCGCCACCGTCTCCATCTGT; AAGAAGTGCATTTACCCCAAGCCAGCCCGAACACACCACTGCAGCATCTGCAACAGGTGT; GTGCTGAAGATGGATCACCACTGCCCCTGGCTAAACAATTGTGTGGGCCACTATAACCAT; CGGTACTTCTTCTCTTTCTGCTTTTTCATGACTCTGGGCTGTGTCTACTGCAGCTATGGA; AGTTGGGACCTTTTCCGGGAGGCTTATGCTGCCATTGAGACTTATCACCAGACCCCACCA; CCCACCTTCTCCTTTCGAGAAAGGATGACTCACAAGAGTCTTGTCTACCTCTGGTTCCTG; TGCAGTTCTGTGGCACTTGCCCCTGGGTGCCCTAACTGTATGGCATGCTGGTCTCATCAG; TCGAGGTGAGACTAGCATCGAAAGCACATCAACANAAGGAGAACGTCCGCT;
• Restriction Sites: Please inquire
• ACCN: NM_198045
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_198045.1, NP_932162.1
• RefSeq Size: 1581 bp
• RefSeq ORF: 891 bp
• Locus ID: 84287
• UniProt ID: Q969W1
• Cytogenetics: 10q24.1
• Protein Families: Transmembrane
• Summary: Palmitoyl acyltransferase that mediates palmitoylation of proteins such as PLN and ZDHHC6 (PubMed:28826475). Required during embryonic heart development and cardiac function, possibly by mediating palmitoylation of PLN, thereby affecting PLN phosphorylation and homooligomerization (By similarity). Also required for eye development (By similarity). Palmitoylates ZDHHC6, affecting the quaternary assembly of ZDHHC6, its localization, stability and function (PubMed:28826475). May play a role in DNA damage response (By similarity). May be involved in apoptosis regulation (By similarity). Involved in the proliferation of neural stem cells by regulating the FGF/ERK pathway (By similarity).[UniProtKB/Swiss-Prot Function]; Transcript Variant: This variant (4) lacks two alternate in-frame exons, one in the 5' coding region and the other in the 3' coding region, compared to variant 5. It encodes isoform 4, which is shorter than isoform 1.