STX1B (NM_052874) Human Untagged Clone

SKU SC120156

STX1B (untagged)-Human syntaxin 1B (STX1B)

Product Data

• Type: Human Untagged Clone
• Target Symbol: STX1B
• Synonyms: GEFSP9; STX1B1; STX1B2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC120156 sequence for NM_052874 edited (data generated by NextGen Sequencing); ATGAAGGATCGGACTCAAGAGCTGCGGAGTGCGAAAGACAGTGATGATGAAGAGGAGGTG; GTCCACGTGGATCGGGACCACTTCATGGATGAGTTCTTTGAACAGGTGGAAGAGATCCGG; GGCTGCATTGAGAAACTGTCGGAGGATGTGGAGCAGGTGAAAAAACAGCATAGCGCCATC; CTGGCCGCACCCAACCCAGATGAGAAGACCAAACAGGAGCTGGAGGATCTCACTGCAGAC; ATCAAGAAGACGGCCAACAAGGTTCGGTCCAAATTGAAAGCGATCGAGCAAAGCATTGAA; CAGGAGGAGGGGCTGAACCGTTCCTCCGCGGACCTGCGCATCCGCAAGACCCAGCACTCC; ACACTGTCCCGGAAGTTCGTGGAGGTAATGACCGAATATAACGCGACCCAGTCCAAGTAC; CGGGACCGCTGCAAGGACCGGATCCAGCGGCAACTGGAGATCACTGGAAGGACCACCACC; AACGAAGAACTGGAAGACATGCTGGAGAGCGGGAAGCTGGCCATCTTCACAGATGACATC; AAAATGGACTCACAGATGACGAAGCAGGCGCTGAATGAGATTGAGACGAGGCACAATGAG; ATCATCAAGCTGGAGACCAGCATCCGCGAGCTGCACGATATGTTTGTGGACATGGCCATG; CTCGTAGAGAGCCAGGGAGAGATGATTGACCGCATCGAGTACAACGTGGAACATTCTGTG; GACTACGTGGAGCGAGCTGTGTCTGACACCAAGAAAGCAGTGAAATATCAGAGCAAGGCC; CGGAGGAAGAAAATCATGATCATCATTTGCTGTGTGGTGCTGGGGGTGGTCTTGGCGTCA; TCCATTGGGGGGACGCTGGGCTTGTAG; ; Clone variation with respect to NM_052874.3;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_052874 unedited; CACACGACTCACTATAGGGCGGCCGCGATTCGGCACGAGGCGCAGCCGCATCGCCACCGC; AGCCCGGCAGAGCCGAGCCCGGCCCAGGCCCCTGCCCCTGCCCGGCCCTCGGCCAGTCGC; CCCCGGCCCCGCCCCCGCCCGCAGGCCCCCCGCAGCGGCCGCGGCGCCCCCCGGCGCCCC; CAGACCCCGGCCTCCGGCACATAGGCGGGAGACCCGGAGCAGCAGCGGAGGCAGGAGGAC; TAGGAGGAGGAGGAGGAGCCGTCGCAGGATGAAGGATCGGACTCAAGAGCTGCGGAGTGC; GAAAGACAGTGATGATGAAGAGGAGGTGGTCCACGTGGATCGGGACCACTTCATGGATGA; GTTCTTTGAACAGGTGGAAGAGATCCGGGGCTGCATTGAGAAACTGTCGGAGGATGTGGA; GCAGGTGAAAAAACAGCATAGCGCCATCCTGGCCGCACCCAACCCAGATGAGAAGACCAA; ACAGGAGCTGGAGGATCTCACTGCAGACATCAAGAAGACGGCCAACAAGGTTCGGTCCAA; ATTGAAAGCGATCGAGCAAAGCATTGAACAGGAGGAGGGGCTGAACCGTTCCTCCGCGGA; CCTGCGCATCCGCAAGACCCAGCACTCCACACTGTCCCCGNAAGTTCGTGGAGGTAATGA; CCGAATATAACGCGACCCAGTCCAAGTCCCGGGACCGTTGCAAGGACCCGGATCCAGCGT; CAACTGGAGATCACTGGGACGTACCCCCACCAACGAATAACTTGGAGACATTGCTGGAGA; GCGGGAAGCTGGCCATCTTTCCAGATGACATCAAAATGGACTTCCCGATGAAGAACCAGG; CGCTGAATGAAATTGAGACCAGGCACCATGAGAACATCAAGTTGTAAACATCTTCCCGCA; AGCTCACAATTTGTTTGTGCACTGCCCTTCTTTTAAAGACCAGGAG;
• Restriction Sites: NotI-NotI
• ACCN: NM_052874
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_052874.1, NP_443106.1
• RefSeq Size: 1709 bp
• RefSeq ORF: 867 bp
• Locus ID: 112755
• UniProt ID: P61266
• Cytogenetics: 16p11.2
• Domains: SynN, t_SNARE
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: SNARE interactions in vesicular transport
• Summary: The protein encoded by this gene belongs to a family of proteins thought to play a role in the exocytosis of synaptic vesicles. Vesicle exocytosis releases vesicular contents and is important to various cellular functions. For instance, the secretion of transmitters from neurons plays an important role in synaptic transmission. After exocytosis, the membrane and proteins from the vesicle are retrieved from the plasma membrane through the process of endocytosis. Mutations in this gene have been identified as one cause of fever-associated epilepsy syndromes. A possible link between this gene and Parkinson's disease has also been suggested. [provided by RefSeq, Jan 2015]