Dopamine Receptor D1 (DRD1) (NM_000794) Human Untagged Clone

SKU SC119692

DRD1 (untagged)-Human dopamine receptor D1 (DRD1)

Product Data

• Type: Human Untagged Clone
• Target Symbol: Dopamine Receptor D1
• Synonyms: DADR; DRD1A
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119692 sequence for NM_000794 edited (data generated by NextGen Sequencing); ATGAGGACTCTGAACACCTCTGCCATGGACGGGACTGGGCTGGTGGTGGAGAGGGACTTC; TCTGTTCGTATCCTCACTGCCTGTTTCCTGTCGCTGCTCATCCTGTCCACGCTCCTGGGG; AACACGCTGGTCTGTGCTGCCGTTATCAGGTTCCGACACCTGCGGTCCAAGGTGACCAAC; TTCTTTGTCATCTCCTTGGCTGTGTCAGATCTCTTGGTGGCCGTCCTGGTCATGCCCTGG; AAGGCAGTGGCTGAGATTGCTGGCTTCTGGCCCTTTGGGTCCTTCTGTAACATCTGGGTG; GCCTTTGACATCATGTGCTCCACTGCATCCATCCTCAACCTCTGTGTGATCAGCGTGGAC; AGGTATTGGGCTATCTCCAGCCCTTTCCGGTATGAGAGAAAGATGACCCCCAAGGCAGCC; TTCATCCTGATCAGTGTGGCATGGACCTTGTCTGTACTCATCTCCTTCATCCCAGTGCAG; CTCAGCTGGCACAAGGCAAAACCCACAAGCCCCTCTGATGGAAATGCCACTTCCCTGGCT; GAGACCATAGACAACTGTGACTCCAGCCTCAGCAGGACATATGCCATCTCATCCTCTGTA; ATAAGCTTTTACATCCCTGTGGCCATCATGATTGTCACCTACACCAGGATCTACAGGATT; GCTCAGAAACAAATACGGCGCATTGCGGCCTTGGAGAGGGCAGCAGTCCACGCCAAGAAT; TGCCAGACCACCACAGGTAATGGAAAGCCTGTCGAATGTTCTCAACCGGAAAGTTCTTTT; AAGATGTCCTTCAAAAGAGAAACTAAAGTCCTGAAGACTCTGTCGGTGATCATGGGTGTG; TTTGTGTGCTGTTGGCTACCTTTCTTCATCTTGAACTGCATTTTGCCCTTCTGTGGGTCT; GGGGAGACGCAGCCCTTCTGCATTGATTCCAACACCTTTGACGTGTTTGTGTGGTTTGGG; TGGGCTAATTCATCCTTGAACCCCATCATTTATGCCTTTAATGCTGATTTTCGGAAGGCA; TTTTCAACCCTCTTAGGATGCTACAGACTTTGCCCTGCGACGAATAATGCCATAGAGACG; GTGAGTATCAATAACAATGGGGCCGCGATGTTTTCCAGCCATCATGAGCCACGAGGCTCC; ATCTCCAAGGAGTGCAATCTGGTTTACCTGATCCCACATGCTGTGGGCTCCTCTGAGGAC; CTGAAAAAGGAGGAGGCAGCTGGCATCGCCAGACCCTTGGAGAAGCTGTCCCCAGCCCTA; TCGGTCATATTGGACTATGACACTGACGTCTCTCTGGAGAAGATCCAACCCATCACACAA; AACGGTCAGCACCCAACCTGA; ; Clone variation with respect to NM_000794.3; 1263 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000794 unedited; GCGGCCGCGAATTCGGCACGAGNAGCGGGCAGTGCCTGCGGGGAGGCGCGGGGCCCTGCT; CTGTAGGGCTGAAGGCCGCCCGAGGTTCGCCAAGGCTCTGGGCTCTCGAAAGGAAGCCAA; GAAAAGAAGCTGCCCAGGTGACCAGTCCTGGGAGTGCTCTCTCCCAAGGAAGCTCCGAGC; GCCCAGGAGCCCTTAGCCGGGGTCTAGTGCCCTTTGAACAATCTCCAGCTCTTCAAGGAA; GTGGGCCGCCGCCGCCTCTCTTGGGACCTGGCCTGAGATCCTTTCCCCAAACGCACCCCG; GCGATTTTTGCGCACCGGGAGCCGAACCCCTGCTGCGCGCAGCTGGCTGGGCTCANGCGC; GCTTCCTCAACGTTTCGAGCCGCTGCCCCAGCGAAGTCACATTTCAGCTCAGCGGCTTTG; GCTATGAGAGACACGACCCCAAGGCAGGGCCGTTGGAAAGCTGCTGAAGACCCAGGGGCT; TGAAAGAACAAAAAAACCTGTTTTTTCAACTGGATTTAAAAAGGGAAAAATCTCCTGTCC; CCCCCAAAAAAGCCCCGCCCCCAAATGGGTTGGCACTGGCTTACAAAACAGGCCCCCGAG; GGCCCGGGTTGGGGGATTTAAAAATTGCCAAAAAACCCCGGCTTTTTTGGGGGGAATTAA; GGGTTTTTTGGGGGCCCCAAAAAGGCCCCTTCCCGGGGGGGGCCAAAAACCACCTGTTAA; AAAAAAAAGGGCCCCCCCCCCGGTTGGTTTGGTGGTTGGCCTTAGGGGGGCTCTTTTTGG; GATGAGGGGAGGGCGCCCCCCCGCGAGGAAAAAAAATTTTTTGTATAAAAAATTCTCCTG; GGGGGGGGGCGCCCCCAAAAAAAACCCGCCCCCCCCTTCCTCTTCCTTAATAAAGAGGGG; GGGGGGCCACCCACTCCGTTCTT;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000794 unedited; CCCCCATTCTGGCTCTCAATGTTCAGTTCATTGCTTATCAACAGGATACGTTGTAAACAT; TTCAAAGAACTCTGTTGAAAGCCCCCGAGTTGGCATCTGGCAAGGGAGGCTTATGATACT; TTTTACAGTCCGGGTGATGATGCAGGAACCTGATTCCAAAGCACAGCAGAAAGGACTAGC; ATTTGTCAAAAGAGATGCTGATGGCTTTGGGGGAGCTCAACACACCCAAAGGGAAGGATT; CTTCTGTTTCTCCCATCAACAGAAGTATCTGACTCAAGAATGATAATGAGGCACTATTCG; TTAGTTAGTATACCATTAACATTTAAAGACTCCTTTAAAAATCAGCTCTAAATTCAGATT; AAAGCACTATAAAAAGTAGCCCCACTGACTGGTTTGGTTTGACCTGGTAAGATGGAAATG; CAGGGTTTGAGTTTGGTCCCTCAGTGGGGCTGCTGTAACCCACTGTCTGTGCTACAGATC; TCTCTCCAGGAAAGCCATTTGTGTGGTTCAGAAAAACTACCTGACACATGAAATGAGAAA; AGATGGAGAGGGCCAATTATTTTACATAAATACAAAGCAGCATATACTTTTCATTACCAC; CTAAGATCGTAAATTTAATGCTGGGCTCTTCTTAAGTTGGCTTTTATTTAAGATATTTAC; AGAACTGCTAATTCCCCTGGGAAAGTCATTTGTCATTTAAAACGTTTTGAACACAGTAGT; AGCTATACTTTTTTAAATATTTCAAAAACTTTTCAGAAAAAGAAAGCATTTATAGCATTT; GTCAATTCTCACCTTGCATTTATCTGTGTCCATGAATTTTAGGCATCATTTCAACTTTAT; TCCTTTATTTATCAGTTTCTGCTGTGTTTTTCAGAGG;
• Restriction Sites: NotI-NotI
• ACCN: NM_000794
• Insert Size: 3800 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_000794.2, NP_000785.1
• RefSeq Size: 2776 bp
• RefSeq ORF: 1341 bp
• Locus ID: 1812
• UniProt ID: P21728
• Cytogenetics: 5q35.2
• Domains: 7tm_1
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Gap junction, Neuroactive ligand-receptor interaction
• Summary: This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. [provided by RefSeq, Jul 2008]