GAPDH (NM_002046) Human Untagged Clone

CAT#: SC118869

GAPDH (untagged)-Human glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

 Cited in 7 publications.

  View "NM_002046" in other vectors (10)

USD 300.00


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Size
    • 10 ug


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Specifications

Product Data
Product Name GAPDH (NM_002046) Human Untagged Clone
Symbol GAPDH
Synonyms G3PD; GAPD; HEL-S-162eP
Vector pCMV6-XL5
Sequence Data
>OriGene ORF sequence for NM_002046 edited
ATGGGGAAGGTGAAGGTCGGAGTCAACGGATTTGGTCGTATTGGGCGCCTGGTCACCAGG
GCTGCTTTTAACTCTGGTAAAGTGGATATTGTTGCCATCAATGACCCCTTCATTGACCTC
AACTACATGGTTTACATGTTCCAATATGATTCCACCCATGGCAAATTCCATGGCACCGTC
AAGGCTGAGAACGGGAAGCTTGTCATCAATGGAAATCCCATCACCATCTTCCAGGAGCGA
GATCCCTCCAAAATCAAGTGGGGCGATGCTGGCGCTGAGTACGTCGTGGAGTCCACTGGC
GTCTTCACCACCATGGAGAAGGCTGGGGCTCATTTGCAGGGGGGAGCCAAAAGGGTCATC
ATCTCTGCCCCCTCTGCTGACGCCCCCATGTTCGTCATGGGTGTGAACCATGAGAAGTAT
GACAACAGCCTCAAGATCATCAGCAATGCCTCCTGCACCACCAACTGCTTAGCACCCCTG
GCCAAGGTCATCCATGACAACTTTGGTATCGTGGAAGGACTCATGACCACAGTCCATGCC
ATCACTGCCACCCAGAAGACTGTGGATGGCCCCTCCGGGAAACTGTGGCGTGATGGCCGC
GGGGCTCTCCAGAACATCATCCCTGCCTCTACTGGCGCTGCCAAGGCTGTGGGCAAGGTC
ATCCCTGAGCTGAACGGGAAGCTCACTGGCATGGCCTTCCGTGTCCCCACTGCCAACGTG
TCAGTGGTGGACCTGACCTGCCGTCTAGAAAAACCTGCCAAATATGATGACATCAAGAAG
GTGGTGAAGCAGGCGTCGGAGGGCCCCCTCAAGGGCATCCTGGGCTACACTGAGCACCAG
GTGGTCTCCTCTGACTTCAACAGCGACACCCACTCCTCCACCTTCGACGCTGGGGCTGGC
ATTGCCCTCAACGACCACTTTGTCAAGCTCATTTCCTGGTATGACAACGAATTTGGCTAC
AGCAACAGGGTGGTGGACCTCATGGCCCACATGGCCTCCAAGGAGTAA
>OriGene 5' read for NM_002046 unedited
ACGAGGTTCGACAGTCAGCCGCATCTTCTTTTGCGTCGCCAGCCGAGCCACATCGCTGAN
ACACCATGGGGAAGGTGAAGGTCGGAGTCAACGGATTTGGTCGTATTGGGCGCCTGGTCA
CCAGGGCTGCTTTTAACTCTGGTAAAGTGGATATTGTTGCCATCAATGACCCCTTCATTG
ACCTCAACTACATGGTTTACATGTTCCAATATGATTCCACCCATGGCAAATTCCATGGCA
CCGTCAAGGCTGAGAACGGGAAGCTTGTCATCAATGGAAATCCCATCACCATCTTCCAGG
AGCGAGATCCCTCCAAAATCAAGTGGGGCGATGCTGGCGCTGAGTACGTCGTGGAGTCCA
CTGGCGTCTTCACCACCATGGAGAAGGCTGGGGCTCATTTGCAGGGGGGAGCCAAAAGGG
TCATCATCTCTGCCCCCTCTGCTGACGCCCCCATGTTCGTCATGGGTGTGAACCATGAGA
AGTATGACAACAGCCTCAAGATCATCAGCAATGCCTCCTGCACCACCAACTGCTTAACAC
CCCTGGCCAAGGGTCATCCATGACAACTTTGGTATCGTGGAAGGACTCATGACCACAGTC
CATGCCATCACTGCCACCCAAAANACTGTGGGATGGCCCCCTNCGGGAAACTGTGGGCGT
GATGGCCCGNGGGGCTCTNCANAACATTATNCCTGCCTNTACTGGGCGCTGCCAAGGCTG
GGGGGCAAGGTCATTCCTTGAACTGAACGGGAANCTCACTGGCATGGGCCTTTCGTGTCC
CCCTGGCAACGTGTTAGGGGGGGGACCTGACCTGCCGTTAAAAAAANCTGCCAAATTGAT
GACCTCAAAAAGGGG
>OriGene 3' read for NM_002046 unedited
TTGGTATGGCAACTTCCAGGNCCAGGTANAGCACTGGGGNAGGGTCACAGGNATGCCACC
CGGGATCTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTT
TTTTTTTTTGGTTGAGCACAGGGTACTTTATTGATGGTACATGACAAGGTGCGGCTCCCT
AGGCCCCTCCCCTCTTCAAGGGGTCTACATGGAAACTGTGAGGAGGGGAGATTCAGTGTG
GTGGGGGACTGAGTGTGGCAGGGACTCCCCAGCAGTGAGGGTCTCTCTCTTCCTCTTGTG
CTCTTGCTGGGGCTGGTGGTCCAGGGGTCTTACTCCTTGGAGGCCATGTGGGCCATGAGG
TCCACCACCCTGTTGCTGTAGCCAAATTCGTTGTCATACCAGGAAATGAGCTTGACAAAG
TGGTCGTTGAGGGCAATGCCAGCCCCAGCGTCNAAGGTGGAGGAGTGGGTGTCGCTGTTG
AAGTCAGAGGAGACCACCTGGTGCTCAGTGTANCCCAGGATGCCCTTGAGGGGGCCCTCC
GACGCCTGCTTCACCACCTTCTTGATGTCATCATATTTGGCAGGTTTTTCTAGACGGCAG
GTCAGGTCCACCACTGACACGTTGGCAGTGGGGACACGGAAGGCCATGCCAGTGAGCTTC
CCGTTCAGCTCAGGGATGACCTTGCCCACAGCCTTGGCAGCGCCAGTAAAGGCAGGGATG
ATGTTCTGGAGACCCCGCNGNCATCACGCACAGTTTCCCGGAGGGGGCATCCACAGTCTT
CTGGGTGCANNGATGGCATGGACCTGTGTCATGATTCCTTCACGATACCCAAAGTGCATG
GATGACCTGGNCAGGGTGCTAA
Restriction Sites NotI-NotI     
Tag Tag Free
ACCN NM_002046
ORF Size 1008 bp
Insert Size 1290
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reference Data
RefSeq NM_002046.2, NP_002037
RefSeq Size 1283
RefSeq ORF 1008
Locus ID 2597
Cytogenetics 12p13.31
Domains gpdh
Protein Families ES Cell Differentiation/IPS
Protein Pathways Glycolysis / Gluconeogenesis, Metabolic pathways, Alzheimer's disease
Gene Summary This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
Transcript Variant: This variant (1) encodes the longer isoform (1).

Citations (7)

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