SOX4 (NM_003107) Human Untagged Clone

SKU SC118160

SOX4 (untagged)-Human SRY (sex determining region Y)-box 4 (SOX4)

Product Data

• Type: Human Untagged Clone
• Target Symbol: SOX4
• Synonyms: CSS10; EVI16
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_003107, the custom clone sequence may differ by one or more nucleotides; ; ; ATGGTGCAGCAAACCAACAATGCCGAGAACACGGAAGCGCTGCTGGCCGGCGAGAGCTCGGACTCGGGCG; CCGGCCTCGAGCTGGGAATCGCCTCCTCCCCCACGCCCGGCTCCACCGCCTCCACGGGCGGCAAGGCCGA; CGACCCGAGCTGGTGCAAGACCCCGAGTGGGCACATCAAGCGACCCATGAACGCCTTCATGGTGTGGTCG; CAGATCGAGCGGCGCAAGATCATGGAGCAGTCGCCCGACATGCACAACGCCGAGATCTCCAAGCGGCTGG; GCAAACGCTGGAAGCTGCTCAAAGACAGCGACAAGATCCCTTTCATTCGAGAGGCGGAGCGGCTGCGCCT; CAAGCACATGGCTGACTACCCCGACTACAAGTACCGGCCCAGGAAGAAGGTGAAGTCCGGCAACGCCAAC; TCCAGCTCCTCGGCCGCCGCCTCCTCCAAGCCGGGGGAGAAGGGAGACAAGGTCGGTGGCAGTGGCGGGG; GCGGCCATGGGGGCGGCGGCGGCGGCGGGAGCAGCAACGCGGGGGGAGGAGGCGGCGGTGCGAGTGGCGG; CGGCGCCAACTCCAAACCGGCGCAGAAAAAGAGCTGCGGCTCCAAAGTGGCGGGCGGCGCGGGCGGTGGG; GTTAGCAAACCGCACGCCAAGCTCATCCTGGCAGGCGGCGGCGGCGGCGGGAAAGCAGCGGCTGCCGCCG; CCGCCTCCTTCGCCGCCGAACAGGCGGGGGCCGCCGCCCTGCTGCCCCTGGGCGCCGCCGCCGACCACCA; CTCGCTGTACAAGGCGCGGACTCCCAGCGCCTCGGCCTCCGCCTCCTCGGCAGCCTCGGCCTCCGCAGCG; CTCGCGGCCCCGGGCAAGCACCTGGCGGAGAAGAAGGTGAAGCGCGTCTACCTGTTCGGCGGCCTGGGCA; CGTCGTCGTCGCCCGTGGGCGGCGTGGGCGCGGGAGCCGACCCCAGCGACCCCCTGGGCCTGTACGAGGA; GGAGGGCGCGGGCTGCTCGCCCGACGCGCCCAGCCTGAGCGGCCGCAGCAGCGCCGCCTCGTCCCCCGCC; GCCGGCCGCTCGCCCGCCGACCACCGCGGCTACGCCAGCCTGCGCGCCGCCTCGCCCGCCCCGTCCAGCG; CGCCCTCGCACGCGTCCTCCTCGGCCTCGTCCCACTCCTCCTCTTCCTCCTCCTCGGGCTCCTCGTCCTC; CGACGACGAGTTCGAAGACGACCTGCTCGACCTGAACCCCAGCTCAAACTTTGAGAGCATGTCCCTGGGC; AGCTTCAGTTCGTCGTCGGCGCTCGACCGGGACCTGGATTTTAACTTCGAGCCCGGCTCCGGCTCGCACT; TCGAGTTCCCGGACTACTGCACGCCCGAGGTGAGCGAGATGATCTCGGGAGACTGGCTCGAGTCCAGCAT; CTCCAACCTGGTTTTCACCTACTGA; ;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003107 unedited; GGATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGCGGTGAGAG; AGCGAGAGAGAGGGAGAGAGAGACTCTCCAGCCTGGGAACTATAACTCCTCTGCGAGAGG; CGGAGAACTCCTTCCCCAAATCTTTTGGGGACTTTTCTCTCTTTACCCACCTCCGCCCCT; GCGAGGAGTTGAGGGGCCAGTTCGGCCGCCGCGCGCGTCTTCCCGTTCGGCGTGTGCTTG; GCCCGGGGAACCGGGAGGGCCCGGCGATCGCGCGGCGGCCGCCGCGAGGGTGTGAGCGCG; CGTGGGCGCCCGCCGAGCCGAGGCCATGGTGCAGCAAACCAACAATGCCGAGAACACGGA; AGCGCTGCTGGCCGGCGAGAGCTCGGACTCGGGCGCCGGCCTCGAGCTGGGAATCGCCTC; CTCCCCCACGCCCGGCTCCACCGCCTCCACGGGCGGCAAGGCCGACGACCCGAGCTGGTG; CAAGACCCCGAGTGGGCACATCAAGCGACCCATGAACGCCTTCATGGTGTGGTCGCAGAT; CGAGCGGCGCAAGATCATGGAGCAGTCGCCCGACATGCACAACGCCGAGATCTCCAAGCG; GCTGGGCAAACGCTGGAAGCTGCTCAAAGACAGCGACAAGATCCCTTTCATTCGAGAGGC; GGAGCGGCTGCGCCTCAAGCACATGGCTGACTACCCCGACTACAAGTACCGGCCCAGGAA; GAAAGTGAAGTCCGGCAACGCCAACTCCAGCTCCTCGGCCGCCGCCTTCTNCAAGCCGGN; GGAGAAGGNANACANNGTCNGTGGCANTGGCGGGGCGGCATTGTGGGGCCCGGCCGCCGC; GCGGGACACCAACCGGGGGAAGGAGGCGCGCGTTCCATTGTCGCCGCCCCACTTCAACCG; CGCANAA;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003107 unedited; TGAGTCGAGTTTTTTTTTTTTTTTTTTTACCTTTTCTCTTTAAACTCTTCGACTGTCCTT; TTCGTTACTTTTTTTCACTTTTTTTTTTCTCCTCTCCTACCCACCCCGGCCCTTCTCCTT; GCCTGCGCGCCCTTCAGTAGGTGAAAACCAGGTTGGAGATGCTGGACTTGAGCCAGCCTC; CCGAGATCATCTCGCTCACCTTGGGCGTGCACCCAGTCGGGAACTCTAAGTGCGAGCCGG; AGCCGGCCTCGAACTTAAAATCCAGGCCCCGGCCCAGCGCCGACGACGAACTGAAGCTGT; TCAGGGACATGCTCTAAAAGTCTGAACTGGGGTTCAGGCCGAGCAGGCCGTCTCCCAACT; CGCTTCTGGAGGACCAGGACCCCCAGGAGGAGGAACAGGAGGAGTGGTACCAGGCCGAGG; AGGACCGCGTGTGAGGGTTCACTGGACGGGGCGGCCGATGCTGATCGCAAGCTGTCGCAA; CCGCGGTGGCCGGTGGTCGACCGGTCGACCCCGGGGGACCAGGAGGAACTGACTGAACCG; CTCAGCCGGCCCCCTTGGTCAGCTCTCCCTCCCCTTTTTTTTCCCGCCCTGGGGCCCACG; GGGCCGTTCCCTTTCCCTCTTGTCCGCTCCCTCCCCCCTCTCTCCCCGTCCGGCTCCTCC; CTTGCCCTCCCCCCCCTCTTCTTTCCCGAGCCCCTCCCCCCCCTCGGTCCCGCTTCTTCG; CGGTTTGTCTCGGCTCTGGCACGCCCCACCTTCCCCCCCGGCGGCCTCCTCCCCCTTCCC; CCCCCCCCACCCGCCCCCGTTAACCCATTCCCAACTGCGCGCTCGCCCTCATTCCCCCTT; CCTCCGGCTCCTTACTTCGCCCGCCCCCCCCCTCTCTTCTCCGTCTCTCCCAATATCGCC; CCCCCTCTACCCCGCTCCCTTTCTCCGTTTTCTATTCCCCGTGCCCCTTCGACCCCCGCT; CCACCCTCCTCTGTCTTCTCCCGCCCGTCCCCCG;
• Restriction Sites: NotI-NotI
• ACCN: NM_003107
• Insert Size: 1840 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_003107.2, NP_003098.1
• RefSeq Size: 4912 bp
• RefSeq ORF: 1425 bp
• Locus ID: 6659
• UniProt ID: Q06945
• Cytogenetics: 6p22.3
• Domains: HMG
• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transcription Factors
• Summary: This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008]