DUSP1 (NM_004417) Human Untagged Clone

SKU
SC117410
DUSP1 (untagged)-Human dual specificity phosphatase 1 (DUSP1)
$457.00
In Stock*
Specifications
Product Data
Type Human Untagged Clone
Target Symbol DUSP1
Synonyms CL100; HVH1; MKP-1; MKP1; PTPN10
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
Fully Sequenced ORF
>OriGene sequence for NM_004417 edited
GAATTCGGCACGGGCGCAGAGAGACCCGGGGGTCTAGCTTTTCCTCGAAAAGCGCCGCCC
TGCCCTTGGCCCCGAGAACAGACAAAGAGCACCGCAGGGCCGATCACGCTGGGGGCGCTG
AGGCCGGCCATGGTCATGGAAGTGGGCACCCTGGACGCTGGAGGCCTGCGGGCGCTGCTG
GGGGAGCGAGCGGCGCAATGCCTGCTGCTGGACTGCCGCTCCTTCTTCGCTTTCAACGCC
GGCCACATCGCCGGCTCTGTCAACGTGCGCTTCAGCACCATCGTGTGGCGCCGGGCCAAG
GGCGCCATGGGCCTGGAGCACATCGTGCCCAACGCCGAGCTCCGCGGCCGCCTGCTGGCC
GGCGCCTACCACGCCGTGGTGTTGCTGGACGAGCGCAGCGCCGCCCTGGACGGCGCCAAG
CGCGACGGCACCCTGGCCCTGGCGGCCGGCGCGCTCTGCCGCGAGGCGCGCGCCGCGCAA
GTCTTCTTCCTCAAAGGAGGATACGAAGCGTTTTCGGCTTCCTGCCCGGAGCTGTGCAGC
AAACAGTCGACCCCCATGGGGCTCAGCCTTCCCCTGAGTACTAGCGTCCCTGACAGCGCG
GAATCTGGGTGCAGTTCCTGCAGTACCCCACTCTACGATCAGGGTGGCCCGGTGGAAATC
CTGCCCTTTCTGTACCTGGGCAGTGCGTATCACGCTTCCCGCAAGGACATGCTGGATGCC
TTGGGCATAACTGCCTTGATCAACGTCTCAGCCAATTGTCCCAACCATTTTGAGGGTCAC
TACCAGTACAAGAGCATCCCTGTGGAGGACAACCACAAGGCAGACATCAGCTCCTGGTTC
AACGAGGCCATTGACTTCATAGACTCCATCAAGAATGCTGGAGGAAGGGTGTTTGTCCAC
TGCCAGGCAGGCATTTCCCGGTCAGCCACCATCTGCCTTGCTTACCTTATGAGGACTAAT
CGAGTCAAGCTGGACGAGGCCTTTGAGTTTGTGAAGCAGAGGCGAAGCATCATCTCTCCC
AACTTCAGCTTCATGGGCCAGCTGCTGCAGTTTGAGTCCCAGGTGCTGGCTCCGCACTGT
TCGGCAGAGGCTGGGAGCCCCGCCATGGCTGTGCTCGACCGAGGCACCTCCACCACCACC
GTGTTCAACTTCCCCGTCTCCATCCCTGTCCACTCCACGAACAGTGCGCTGAGCTACCTT
CAGAGCCCCATTACGACCTCTCCCAGCTGCTGAAAGGCCACGGGAGGTGAGGCTCTTCAC
ATCCCATTGGGACTCCATGCTCCTTGAGAGGAGAAATGCAATAACTCTGGGAGGGGCTCG
AGAGGGCTGGTCCTTATTTATTTAACTTCACCCGAGTTCCTCTGGGTTTCTAAGCAGTTA
TGGTGATGACTTAGCGTCAAGACATTTGCTGAACTCAGCACATTCGGGACCAATATATAG
TGGGTACATCAAGTCCATCTGACAAAATGGGGCAGAAGAGAAAGGACTCAGTGTGTGATC
CGGTTTCTTTTTGCTCGCCCCTGTTTTTTGTAGAATCTCTTCATGCTTGACATACCTACC
AGTATTATTCCCGACGACACATATACATATGAGAATATACCTTATTTATTTTTGTGTAGG
TGTCTGCCTTCACAAATGTCATTGTCTACTCCTAGAAGAACCAAATACCTCAATTTTTGT
TTTTGAGTACTGTACTATCCTGTAAATATATCTTAAGCAGGTTTGTTTTCAGCACTGATG
GAAAATACCAGTGTTGGGTTTTTTTTTAGTTGCCAACAGTTGTATGTTTGCTGATTATTT
ATGACCTGAAATAATATATTTCTTCTTCTAAGAAGACATTTTGTTACATAAGGATGACTT
TTTTATACAATGGAATAAATTATGGCATTTCTATTGAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAACTCGAC
5' Read Nucleotide Sequence
>OriGene 5' read for NM_004417 unedited
CAAAATTGTATACGACTCACTATAGGGCGGCCGCGAATTCGCACGGGCGCAGAGAGACCC
GGGGGTCTAGCTTTTCCTCGAAAGCGCCGCCCTGCCCTTGGCCCCGAGAACAGACAAAGA
GCACCGCAGGGCCGATCACGCTGGGGGCGCTGAGGCCGGCCATGGTCATGGAAGTGGGCA
CCCTGGACGCTGGAGGCCTGCGGGCGCTGCTGGGGGAGCGAGCGGCGCAATGCCTGCTGC
TGGACTGCCGCTCCTTCTTCGCTTTCAACGCCGGCCACATCGCCGGCTCTGTCAACGTGC
GCTTCAGCACCATCGTGTGGCGCCGGGCCAAGGGCGCCATGGGCCTGGAGCACATCGTGC
CCAACGCCGAGCTCCGCGGCCGCCTGCTGGCCGGCGCCTACCACGCCGTGGTGTTGCTGG
ACGAGCGCAGCGCCGCCCTGGACGGCGCCAAGCGCGACGGCACCCTGGCCCTGGCGGCCG
GCGCGCTCTGCCGCGAGGCGCGCGCCGCGCAAGTCTTCTTCCTCAAAGGAGGATACGAAG
CGTTTTCGGCTTCCTGCCCGGAGCTGTGCAGCAAACAGTCGACCCCCATGGGGCTCAGCC
TTCCCCTGAGTACTAGCGTCCCTGACAGCGCGGAATCTGGGTGCAGTTCCTGCAGTACCC
CACTCTACGATCAGGGTGGCCCGGTGGAAATCCTGCCCTTTCTGTACCTGGGCAGTGCGT
ATCACGCTTCCCGCAGGACATGCTGGATGCCTTGGCATAACTGCCTTGATCAACGTCTCA
GCCAATTGTCCCACCATTTTTGGGGTCACTACCAGTACAGAGCATCCCGGTGGGAGACAC
CCCCAAGCAGACTCAGCTCCTGGTTAACGAGCCATTGACTCATAACTCATCAGAGCTGAG
GAAAGGGGGGTGGTCCACTGCAGCAGCATTCN
3' Read Nucleotide Sequence
>OriGene 3' read for NM_004417 unedited
AATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTCCAATAAAAATGCCA
TAATTTATTCCATTGTATAAAAAAGTCATCCTTATGTAACAAAATGTCTTCTTAAAAAAA
AAAATATATTATTTCAGGTCATAAATAATCAGCAAACATACAACTGTTGGCAACTAAAAA
AAAACCCAACACTGGTATTTTCCATCAGGGCTGAAAACAAACCTGCTTAAAATATATTTA
CAGGATAGTACAGTCCTCAAAAACAAAAATTGAGGTATTTGGTTCTTCTAGGAGTAAACA
ATGACATTTGTGAAGGCAAACCCCTACACAAAAATAAATAAGGTATATTCTCATATGTAT
ATGGGCCGCCGGGAATAATACTGGTAGGTATGTCAAGCATGAAAAGATTCTACAAAAAAC
AGGGGCGAGCAAAAAGAAACCGGATCACACACTGAGTCCTTTCTCTTCTGCCCCATTTTG
TCAAATGGACTTGATGTACCCACTATATATTGGTCCCGAATGTGCTGAGTTCAGCAAATG
TCTTGACGCTAAGTCATCACCATAACTGCTTAGAAACCCAGAGGAACTCGGGTGAAGTTA
AATAAATAAGGACCAGCCCTCTAGAGCCCTTCCCAGATTATTGCATTTCTCCTCTCAAGA
GCATGGAGTCCCAATGGGATGTGAAGAGCCTCACCTCCCGTGGCCTTTCANCAGCTGGGA
AAAGGTCCTAATGGGGCTCTGAAGGTANCTCACCCCCCTTGTTCTGGAGTGAACAGGGAT
GGAACCGGGAANTTAACANCGGGGTGGTGGAGGTGCTTCGTCCAACCAGCCTGCGGGGCT
CCCACCTTTGCCAAAGTGCGAACCACACCTGGACTTAATGCNACACTGCCCATGAATTAA
TTGGGAAATTATCTCCTCTTGTTAAAAATAAAGGCTTGCCACTTGCTCCATATCCCTAAG
GAACAAGCAAATGGGCTACCGAAATCCTCTGAATG
Restriction Sites NotI-NotI
ACCN NM_004417
Insert Size 1104 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Components The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution Method 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Note Plasmids are not sterile.  For experiments where strict sterility is required, filtration with 0.22um filter is required.
Shipping Ambient
Reference Data
RefSeq NM_004417.2, NP_004408.1
RefSeq Size 2015 bp
RefSeq ORF 1104 bp
Locus ID 1843
UniProt ID P28562
Cytogenetics 5q35.1
Domains DSPc, PTPc_motif, RHOD
Protein Families Druggable Genome, Phosphatase
Protein Pathways MAPK signaling pathway
Summary The protein encoded by this gene is a phosphatase with dual specificity for tyrosine and threonine. The encoded protein can dephosphorylate MAP kinase MAPK1/ERK2, which results in its involvement in several cellular processes. This protein appears to play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. Finally, the encoded protein can make some solid tumors resistant to both chemotherapy and radiotherapy, making it a target for cancer therapy. [provided by RefSeq, Aug 2017]
Write Your Own Review
You're reviewing:DUSP1 (NM_004417) Human Untagged Clone
Your Rating
SKU Description Size Price
RC205220 DUSP1 (Myc-DDK-tagged)-Human dual specificity phosphatase 1 (DUSP1) 10 ug
$457.00
RC205220L1 Lenti ORF clone of Human dual specificity phosphatase 1 (DUSP1), Myc-DDK-tagged 10 ug
$757.00
RC205220L2 Lenti ORF clone of Human dual specificity phosphatase 1 (DUSP1), mGFP tagged 10 ug
$757.00
RC205220L3 Lenti ORF clone of Human dual specificity phosphatase 1 (DUSP1), Myc-DDK-tagged 10 ug
$757.00
RC205220L4 Lenti ORF clone of Human dual specificity phosphatase 1 (DUSP1), mGFP tagged 10 ug
$757.00
RG205220 DUSP1 (tGFP-tagged) - Human dual specificity phosphatase 1 (DUSP1) 10 ug
$489.00 MSRP $657.00 MSRP $657.00

Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.