ZCWCC1 (MORC2) (NM_014941) Human Untagged Clone

CAT#: SC114779

MORC2 (untagged)-Human MORC family CW-type zinc finger 2 (MORC2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ZCWCC1
• Synonyms: CMT2Z; DIGFAN; ZCW3; ZCWCC1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC114779 sequence for NM_014941 edited (data generated by NextGen Sequencing)
  ATGCTTTGCTTTTTGGATGATGGAGCAGGAATGGATCCAAGTGATGCTGCCAGTGTGATC
  CAGTTTGGGAAGTCGGCCAAGCGAACACCTGAGTCTACTCAGATTGGGCAGTACGGGAAT
  GGGTTAAAATCGGGCTCAATGCGCATTGGGAAGGATTTTATCCTGTTCACCAAGAAGGAA
  GACACCATGACCTGCCTCTTCCTGTCTCGCACGTTTCATGAGGAAGAAGGCATTGATGAA
  GTGATAGTCCCACTGCCCACCTGGAATGCTCGGACCCGGGAACCTGTCACAGACAATGTA
  GAGAAATTTGCCATTGAGACAGAACTCATCTATAAGTACTCTCCATTCCGCACTGAGGAG
  GAAGTGATGACCCAGTTTATGAAGATTCCTGGGGACAGCGGAACATTGGTGATCATCTTC
  AATCTCAAACTCATGGATAATGGAGAGCCAGAACTAGACATAATCTCAAATCCAAGAGAT
  ATCCAGATGGCAGAGACGTCCCCAGAGGGCACGAAGCCAGAGCGGCGCTCGTTCCGTGCC
  TATGCCGCTGTGCTCTATATTGATCCCCGGATGAGGATCTTCATCCATGGGCACAAGGTG
  CAGACCAAGAGGCTCTCCTGCTGCCTGTACAAGCCCAGGATGTACAAGTACACGTCAAGC
  CGTTTCAAGACCCGTGCGGAGCAGGAGGTGAAGAAAGCAGAGCACGTAGCAAGGATTGCT
  GAAGAGAAGGCGCGGGAGGCAGAGAGCAAAGCTCGGACATTAGAAGTACGCCTAGGTGGA
  GACCTCACGCGGGACTCCAGGGTGATGTTGCGACAGGTCCAGAACAGAGCCATCACTCTG
  CGCAGAGAAGCCGATGTCAAGAAGAGGATCAAGGAGGCCAAGCAGCGAGCACTTAAAGAA
  CCTAAGGAACTGAATTTTGTTTTTGGTGTCAACATTGAACACCGGGATCTGGATGGCATG
  TTCATCTACAACTGTAGCCGACTGATCAAAATGTATGAGAAAGTGGGCCCACAGCTGGAA
  GGGGGCATGGCATGTGGCGGGGTTGTTGGGGTTGTTGATGTGCCCTACCTGGTCCTGGAG
  CCTACACACAACAAACAGGACTTTGCTGATGCCAAGGAGTACCGGCACCTGCTCCGAGCA
  ATGGGGGAGCACCTGGCGCAGTATTGGAAGGATATTGCCATCGCCCAGAGGGGAATCATC
  AAGTTCTGGGATGAGTTTGGCTACCTCTCTGCCAACTGGAACCAGCCCCCATCCAGTGAG
  CTGCGTTACAAACGCCGGAGAGCTATGGAAATCCCCACCACCATCCAGTGCGATTTGTGT
  CTGAAATGGAGAACCCTCCCCTTCCAGCTGAGTTCTGTGGAAAAAGATTACCCTGACACC
  TGGGTTTGCTCCATGAACCCTGATCCTGAACAGGACCGGTGTGAGGCTTCTGAACAAAAG
  CAGAAGGTTCCCCTGGGAACATTCAGAAAGGACATGAAGACGCAGGAAGAGAAGCAGAAA
  CAACTGACAGAGAAAATTCGCCAGCAGCAGGAGAAGCTGGAGGCCCTTCAGAAAACCACA
  CCCATCCGCTCCCAAGCAGACCTGAAGAAATTGCCCTTGGAAGTGACCACCAGACCTTCC
  ACTGAGGAACCTGTGCGTAGACCTCAGCGTCCTCGGTCGCCCCCTTTACCTGCTGTGATC
  AGGAACGCCCCCAGCAGACCCCCTTCTTTGCCAACTCCTAGACCAGCCAGCCAGCCCCGA
  AAGGCTCCTGTCATCAGCAGTACCCCAAAGCTCCCTGCTTTGGCAGCCCGGGAGGAGGCC
  AGCACATCTAGGCTGCTCCAGCCACCTGAGGCACCCCGAAAGCCTGCCAACACTCTCGTC
  AAGACTGCATCCCGACCTGCCCCTCTGGTGCAGCAACTGTCACCATCTTTACTGCCCAAC
  TCCAAGAGCCCTCGGGAGGTTCCTTCTCCCAAAGTCATCAAGACTCCAGTGGTGAAGAAG
  ACAGAGTCACCCATCAAACTCTCCCCGGCTACCCCTAGTCGGAAGCGGAGTGTCGCAGTT
  TCTGATGAGGAAGAAGTTGAGGAGGAAGCTGAGAGGAGGAAGGAGAGGTGCAAGCGGGGC
  AGATTTGTTGTGAAGGAGGAAAAGAAGGACTCGAATGAGCTCTCAGACAGTGCTGGGGAA
  GAGGACTCGGCTGACCTCAAGAGAGCTCAGAAAGATAAAGGGCTGCACGTGGAGGTGCGT
  GTGAACAGGGAGTGGTACACGGGCCGTGTCACAGCCGTGGAGGTGGGCAAGCATGTGGTG
  CGGTGGAAGGTGAAGTTTGACTACGTGCCCACAGACACGACACCAAGAGACCGCTGGGTG
  GAGAAAGGCAGTGAGGATGTGCGGCTGATGAAACCCCCTTCTCCGGAACATCAGAGCCTT
  GATACACAACAGGAGGGCGGGGAGGAGGAGGTGGGCCCTGTGGCCCAGCAGGCCATAGCT
  GTCGCAGAGCCCTCCACTTCCGAATGCCTCCGCATTGAGCCTGACACCACTGCCCTGAGC
  ACCAATCACGAGACCATCGACCTGCTTGTCCAGATCCTCCGGAATTGTTTACGGTACTTC
  CTGCCTCCAAGTTTCCCCATCTCCAAGAAGCAGCTGAGTGCTATGAATTCAGATGAGCTA
  ATATCTTTTCCTCTGAAGGAGTACTTCAAGCAATATGAAGTAGGGCTCCAAAACCTGTGC
  AATTCCTACCAGAGCCGTGCTGACTCCCGGGCCAAGGCCTCCGAGGAAAGCCTGCGCACC
  TCCGAGAGGAAGCTCCGCGAGACGGAGGAGAAGCTGCAGAAGCTGAGGACCAACATCGTG
  GCACTCCTGCAAAAGGTGCAGGAGGACATAGACATCAACACAGATGATGAGCTGGACGCC
  TACATTGAGGACCTCATCACCAAGGGGGACTGA
  
  Clone variation with respect to NM_014941.1
  192 g=>c;1251 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_014941 unedited
  GCATTAGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGGACCATCTCCTTC
  AGGACCATCCACACGAGAATCAGATTGTCTGAATTGAGCTATCGCAACTTAATGCTAAAA
  GCTCCTTAAAGCTACAGATTTATGACATAGTTCCTTCCAAAATATTACATCATAAATCAT
  TGAGAAGATTAAAAAAAAACACTTGAAGAAATTGTAGTTTTAAACATCTCTGCATATATT
  TTGGATAGCTACTAGGTTACTTTAACTGTCATTAAGGAGCACAGACTTACTGAAGCTTTA
  CTGGACAGAATCCTGGGAAATCGATATCATTATAAGGTTATATTTCCCAGTTAGCGGGTG
  AAGGGCTGGAGACCTTATTGCAGTCATGGCTTTCACAAATTACAGCAGTCTGAATCGAGC
  TCAGCTAACCTTTGAATATCTGCACACAAATTCAACCACTCACGAATTCTTGTTTGGTGC
  CCTTGCTGAACTGGTTGATAATGCAAGAGATGCTGATGCCACCAGAATAGATATTTATGC
  AGAAAGACGAGAGGACCTTCGAGGAGGATTTATGCTNTGCTTTTTGGATGATGGAGCAGG
  AATGGATCCAAGTGATGCTGCCAGTGTGATCCAGTTTGGGAAGTCGGCCAAGCGAACACC
  TGAGTCTACTCAGATTGGGCAGTACGGGAATGGGTTANAAATCGGCTCAATGCGCATTGN
  GAANGGATTTTATCCTGTTCACCAAGAAGGAAGACACCATGACCTGCCTCTTCCTGTCTC
  GCACGTTTCATGAGGAANAAAGCATTGATGAAGTGATAGTCCCACTGCCCACCTGGAATG
  CTCCNACCCGGGAAACCTGTCACAGACAATGTAGNAGAATATTTCCATTGAGACAGACTT
  CATCTATAGTACTCTCCCATTCGCACTCGAGAGGAAGTGATGACCCAGTTTATTGAGATT
  CCTGGGGAAGCGNAACATTGTGAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_014941 unedited
  TATGCCTCGCACTCCGCATTCCTAAAGTCGAGTTTTTTTTTTTTTTTTTTCTTTTAAAAA
  TAATATTTATAAACTTAGGAAGATCAAAGAATCAGGGTATCTTTTCCTCCAAAAACACAA
  ATGTCCCGTGTAAGTCAAACCAAGGTGCGACCACCAACCCATGAATGAAGTCCCCTCCCC
  CTGCAGCTACAGGGTTGAGGGGCAGGTGGGCAGGGGAGCTGCTCTCTCTCCTGCCTTCAG
  TCCCCCTTGGCGATGAGGTCCTCAATGTAGGCGTCCAGCTCATCATCTGTGTTGATGTCT
  ATGTCCTCCTGCACCTTTTGCAGGAGTGCCACGATGTTGGCCCTCAGCTTCTGCAGCTTC
  TCCTCCGTCTCGCGGAGCTTCCTCTCGGAGGTGCGCAGGCTTTCCTCGGAGGCCTTGGCC
  CGGGAGTCAGCACGGCTCTGGTAGGAATTGCACAGGTTTCGGAGCCCTACTTCATATTGC
  TTGAACCACTCCTCCACAGGACCAGATATTACCTCATCTGAACCCCTACACTCAGCTGCT
  TCTTGCCATGCCCACACCTGGAGGCCAGAGTCACCGTACCCATTCCGGCGGACCCGGACC
  AGCGGTCCACGGCCCTCGTGATTGGTGCTCATGCCCCCGGCGTTACCTTCAACGTGGCAG
  CCCTCCGTAACCGCAGGCCTCCGCGACAGTTATGCCCTGTCTGGGCACACGCCCCCCCTT
  CCTTATTGACACTTCCCGTTCGCTTCCCAAGCCCTTGATGTTTTCCGAAAATGCGGTCGG
  ACGCGCACGGACAACCCTGCTGGCTTTACCTTCACCAATCCCTCCCCTTCCATATAAACG
  CCCGGTCTCTTCCCTCGATTTTCGCTTCCCGCCGTTCCCCCGCTTTCCGCCCCTCCGCCG
  TTGAACCGAAGCCCCAGCCATCCCCTATAACCCGACCACAGTGCAACGAGGATTTTTCCC
  ATCCCTTCTCCTGCTATCCATAACATTCTTTTTCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014941
• Insert Size: 3890 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_014941.1, NP_055756.1
• RefSeq Size: 4467 bp
• RefSeq ORF: 2913 bp
• Locus ID: 22880
• UniProt ID: Q9Y6X9
• Cytogenetics: 22q12.2
• Gene Summary: This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in repressing transcription. The protein has been found to regulate the activity of ATP citrate lyase via specific interaction with this enzyme in the cytosol of lipogenic breast cancer cells. The protein also plays a role in lipogenesis and adipocyte differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]
  Transcript Variant: This variant (3) has an additional exon which results in the use of an in-frame downstream start codon, compared to variant 1. This difference results in an isoform (3) with a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.