ZCWCC1 (MORC2) (NM_014941) Human Untagged Clone

CAT#: SC320309

MORC2 (untagged)-Human MORC family CW-type zinc finger 2 (MORC2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ZCWCC1
• Synonyms: CMT2Z; DIGFAN; ZCW3; ZCWCC1
• Vector: pCMV6-AC
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: Neomycin
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_014941.1 CACGAATTCTTGTTTGGTGCCCTTGCTGAACTGGTTGATAATGCAAGAGATGCTGATGCC
  ACCAGAATAGATATTTATGCAGAAAGACGAGAGGACCTTCGAGGAGGATTTATGCTTTGC
  TTTTTGGATGATGGAGCAGGAATGGATCCAAGTGATGCTGCCAGTGTGATCCAGTTTGGG
  AAGTCGGCCAAGCGAACACCTGAGTCTACTCAGATTGGGCAGTACGGGAATGGGTTAAAA
  TCGGGCTCAATGCGCATTGGGAAGGATTTTATCCTGTTCACCAAGAAGGAAGACACCATG
  ACCTGCCTCTTCCTGTCTCGCACGTTTCATGAGGAAGAAGGCATTGATGAAGTGATAGTC
  CCACTGCCCACCTGGAATGCTCGGACCCGGGAACCTGTCACAGACAATGTAGAGAAATTT
  GCCATTGAGACAGAACTCATCTATAAGTACTCTCCATTCCGCACTGAGGAGGAAGTGATG
  ACCCAGTTTATGAAGATTCCTGGGGACAGCGGAACATTGGTGATCATCTTCAATCTCAAA
  CTCATGGATAATGGAGAGCCAGAACTAGACATAATCTCAAATCCAAGAGATATCCAGATG
  GCAGAGACGTCCCCAGAGGGCACGAAGCCAGAGCGGCGCTCGTTCCGTGCCTATGCCGCT
  GTGCTCTATATTGATCCCCGGATGAGGATCTTCATCCATGGGCACAAGGTGCAGACCAAG
  AGGCTCTCCTGCTGCCTGTACAAGCCCAGGATGTACAAGTACACGTCAAGCCGTTTCAAG
  ACCCGTGCGGAGCAGGAGGTGAAGAAAGCAGAGCACGTAGCAAGGATTGCTGAAGAGAAG
  GCGCGGGAGGCAGAGAGCAAAGCTCGGACATTAGAAGTACGCCTAGGTGGAGACCTCACG
  CGGGACTCCAGGGTGATGTTGCGACAGGTCCAGAACAGAGCCATCACTCTGCGCAGAGAA
  GCCGATGTCAAGAAGAGGATCAAGGAGGCCAAGCAGCGAGCACTTAAAGAACCTAAGGAA
  CTGAATTTTGTTTTTGGTGTCAACATTGAACACCGGGATCTGGATGGCATGTTCATCTAC
  AACTGTAGCCGACTGATCAAAATGTATGAGAAAGTGGGCCCACAGCTGGAAGGGGGCATG
  GCATGTGGCGGGGTTGTTGGGGTTGTTGATGTGCCCTACCTGGTCCTGGAGCCTACACAC
  AACAAACAGGACTTTGCTGATGCCAAGGAGTACCGGCACCTGCTCCGAGCAATGGGGGAG
  CACCTGGCGCAGTATTGGAAGGATATTGCCATCGCCCAGAGGGGAATCATCAAGTTCTGG
  GATGAGTTTGGCTACCTCTCTGCCAACTGGAACCAGCCCCCATCCAGTGAGCTGCGTTAC
  AAACGCCGGAGAGCTATGGAAATCCCCACCACCATCCAGTGCGATTTGTGTCTGAAATGG
  AGAACCCTCCCCTTCCAGCTGAGTTCTGTGGAAAAAGATTACCCTGACACCTGGGTTTGC
  TCCATGAACCCTGATCCTGAACAGGACCGGTGTGAGGCTTCTGAACAAAAGCAGAAGGTT
  CCCCTGGGAACATTCAGAAAGGACATGAAGACGCAGGAAGAGAAGCAGAAACAACTGACA
  GAGAAAATTCGCCAGCAGCAGGAGAAGCTGGAGGCCCTTCAGAAAACCACACCCATCCGC
  TCCCAAGCAGACCTGAAGAAATTGCCCTTGGAAGTGACCACCAGACCTTCCACTGAGGAA
  CCTGTGCGTAGACCTCAGCGTCCTCGGTCGCCCCCTTTACCTGCTGTGATCAGGAACGCC
  CCCAGCAGACCCCCTTCTTTGCCAACTCCTAGACCAGCCAGCCAGCCCCGAAAGGCTCCT
  GTCATCAGCAGTACCCCAAAGCTCCCTGCTTTGGCAGCCCGGGAGGAGGCCAGCACATCT
  AGGCTGCTCCAGCCACCTGAGGCACCCCGAAAGCCTGCCAACACTCTCGTCAAGACTGCA
  TCCCGACCTGCCCCTCTGGTGCAGCAACTGTCACCATCTTTACTGCCCAACTCCAAGAGC
  CCTCGGGAGGTTCCTTCTCCCAAAGTCATCAAGACTCCAGTGGTGAAGAAGACAGAGTCA
  CCCATCAAACTCTCCCCGGCTACCCCTAGTCGGAAGCGGAGTGTCGCAGTTTCTGATGAG
  GAAGAAGTTGAGGAGGAAGCTGAGAGGAGGAAGGAGAGGTGCAAGCGGGGCAGATTTGTT
  GTGAAGGAGGAAAAGAAGGACTCGAATGAGCTCTCAGACAGTGCTGGGGAAGAGGACTCG
  GCTGACCTCAAGAGAGCTCAGAAAGATAAAGGGCTGCACGTGGAGGTGCGTGTGAACAGG
  GAGTGGTACACGGGCCGTGTCACAGCCGTGGAGGTGGGCAAGCATGTGGTGCGGTGGAAG
  GTGAAGTTTGACTACGTGCCCACAGACACGACACCAAGAGACCGCTGGGTGGAGAAAGGC
  AGTGAGGATGTGCGGCTGATGAAACCCCCTTCTCCGGAACATCAGAGCCTTGATACACAA
  CAGGAGGGCGGGGAGGAGGAGGTGGGCCCTGTGGCCCAGCAGGCCATAGCTGTCGCAGAG
  CCCTCCACTTCCGAATGCCTCCGCATTGAGCCTGACACCACTGCCCTGAGCACCAATCAC
  GAGACCATCGACCTGCTTGTCCAGATCCTCCGGAATTGTTTACGGTACTTCCTGCCTCCA
  AGTTTCCCCATCTCCAAGAAGCAGCTGAGTGCTATGAATTCAGATGAGCTAATATCTTTT
  CCTCTGAAGGAGTACTTCAAGCAATATGAAGTAGGGCTCCAAAACCTGTGCAATTCCTAC
  CAGAGCCGTGCTGACTCCCGGGCCAAGGCCTCCGAGGAAAGCCTGCGCACCTCCGAGAGG
  AAGCTCCGCGAGACGGAGGAGAAGCTGCAGAAGCTGAGGACCAACATCGTGGCACTCCTG
  CAAAAGGTGCAGGAGGACATAGACATCAACACAGATGATGAGCTGGACGCCTACATTGAG
  GACCTCATCACCAAGGGGGACTGAAGGCAGGAGAGAGAGCAGCTCCCCTGCCCACCTGCC
  CCTCAACCCTGTAGCTGCAGGGGGAGGGGACTTCATTCATGGGTTGGTGGTCGCACCTTG
  GTTTGACTTACACGGGACATTTGTGTTTTTGGAGGAAAAGATACCCTGATTCTTTGAATC
  TTCCTTAAGTTTATAAATATTTATTTTTTAAAAGAAAAAAAAAAAAAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACCCTGGG
  G
• Restriction Sites: Please inquire
• ACCN: NM_014941
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_014941.1, NP_055756.1
• RefSeq Size: 4467 bp
• RefSeq ORF: 2913 bp
• Locus ID: 22880
• UniProt ID: Q9Y6X9
• Cytogenetics: 22q12.2
• Gene Summary: This gene encodes a member of the Microrchidia (MORC) protein superfamily. The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in repressing transcription. The protein has been found to regulate the activity of ATP citrate lyase via specific interaction with this enzyme in the cytosol of lipogenic breast cancer cells. The protein also plays a role in lipogenesis and adipocyte differentiation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]
  Transcript Variant: This variant (3) has an additional exon which results in the use of an in-frame downstream start codon, compared to variant 1. This difference results in an isoform (3) with a shorter N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.