PGEA1 (CBY1) (NM_015373) Human Untagged Clone

SKU SC114725

CBY1 (untagged)-Human chibby homolog 1 (Drosophila) (CBY1), transcript variant 1

Product Data

• Type: Human Untagged Clone
• Target Symbol: PGEA1
• Synonyms: arb1; C22orf2; CBY; Chibby1; HS508I15A; PGEA1; PIGEA-14; PIGEA14
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_015373, the custom clone sequence may differ by one or more nucleotides; ; ; ATGCCTTTCTTTGGGAATACGTTCAGTCCGAAGAAGACACCTCCTCGGAAGTCGGCATCTCTCTCCAACC; TGCATTCTTTGGATCGATCAACCCGGGAGGTGGAGCTGGGCTTGGAATACGGATCCCCGACTATGAACCT; GGCAGGGCAAAGCCTGAAGTTTGAAAATGGCCAGTGGATAGCAGAGACAGGGGTTAGTGGCGGTGTGGAC; CGGAGGGAGGTTCAGCGCCTTCGCAGGCGGAACCAGCAGTTGGAGGAAGAGAACAATCTCTTGCGGCTGA; AAGTGGACATCTTATTAGACATGCTTTCAGAGTCCACTGCTGAATCCCACTTAATGGAGAAGGAACTGGA; TGAACTGAGGATCAGCCGGAAGAGAAAATGA; ;
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_015373 unedited; GTATACGACTCACTATAGGCGGCCCGCGATTCGGCACGAGGAGGGAGCACTGGCTTTGCT; TTCATCAGGCCAAAGAGCCTTTCTTTGGGAATACGTTCAGTCCGAAGAAGACACCTCCTC; GGAAGTCGGCATCTCTCTCCAACCTGCATTCTTTGGATCGATCAACCCGGGAGGTGGAGC; TGGGCTTGGAATACGGATCCCCGACTATGAACCTGGCAGGGCAAAGCCTGAAGTTTGAAA; ATGGCCAGTGGATAGCAGAGACAGGGGTTAGTGGCGGTGTGGACCGGAGGGAGGTTCAGC; GCCTTCGCAGGCGGAACCAGCAGTTGGAGGAAGAGAACAATCTCTTGCGGCTGAAAGTGG; ACATCTTATTAGACATGCTTTCAGAGTCCACTGCTGAATCCCACTTAATGGAGAAGGAAC; TGGATGAACTGAGGATCAGCCGGAAGAGAAAATGAAGACCCCAGAGACATTTATTGGGGA; GTAGGATGTGGCTGAGTGCTTTTTTTTTGGCCAGACTAGCGGATTCAGTCCTGGAAGAGA; GTATCATATAATGAGACCCACAGGCACTGGCACCCTTGGGTTGGCAATAGAAGGTGACAT; GGAATGGAGAAAACCAAGATTCCAGATGGGGATAGTAACTAGAAGGTGCTTCAGATGCAC; TGCCTGCGGGTGCCAGTCTGAAAACCAGACCGCACAGAGGCCTGNGGGCTGCTGATGAGC; CTTTTTGGTGCTCTCCACACACAAGCTCGCAAACACACATGTCCCAAATAGCTCTGNTGG; NGNNTTGTGTGGGAAGAGCGNCTGNAGNTCATTCTCTCACCCCCTATGTTNGTGTTTGGC; GTGTGACAGCAGTCTACGAGCTCTGGGTTGGGGTCATGAATGAACGGCTCTCCTTGCTCT; TAAGGNCAGCCTCTCTTTTCTTGCTTAAN;
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_015373 unedited; GCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTATTTAACATCGTTTAATAAAAAA; GTAGTAGTGCAAACAGGAAAGTAGCATAAAAATATAGTGTTGTTGTGGAAGGCTGGTGCT; TGCTGCTGAGAAGCTGAAGCCAGAGGAGGCCAGGTGTGAGGAAGGAGGATTCTTTAAAGG; CAAGAAGAGAGAGGCCTGCCTTTAAGAGCCAAGAGAGCCGCTCATCCATGACCCCAACAC; AGAGCTCTGTAGAACTGCTGTCACACGCCAAACACCAACATAAGGGGGTGAGAGAATGAA; CTCCAGCCGCTTCTCCCAACACAACCCAACAGAGCTATTCTGGGACATGTGTGTTTGCGA; GCTTGTGTGTGGAGAGCACCAAAAAGCTCATCAGCAGCCCCAGGCCTCTGTGCGGTCTGG; TTTTCAGACTGGCACCCGCAGGCAGTGCATCTGAAGCACCTTCTAGTTACTATCCCCATC; TGGAATCTTGGTTTTCTCCATTCCATGTCACCTTCTATTGCCAACCCAAGGGTGCCAGTG; CCTGTGGGTCTCATTATATGATACTCTCTTCCAGGACTGAATCCGCTAGTCTGGCCAAAA; AAAAAGCACTCAGCCACATCCTACTCCCCAATAAATGTCTCTGGGGTCTTCATTTTCTCT; TCCGGCTGATCCTCAGTTCATCCAGTTCCTTCTCCATTAAGTGGGATTCAGCAGTGGACT; CTGAAAGCATGTCTAATAAGATGTCCACTTNTCAGCCGCAGAGATGGTCCTCTTCCTCCA; ACTGCTGGGTCCGCCTGCGAAAGCGCTGAACCTCCCTTCGGTNCACACCGCCACTAACCC; CTGTCTCTGCTATCCCTGGCCATTTCAAACTCAGGCTTTGCCTGCCAGTTCATATTCGGG; GATCCGATTCCAGCCCAGCTCCCTCCCGGGTTGATCGATCAAAAATGCGGTTGGAGAAGA; TGCGCTTCCGAG;
• Restriction Sites: NotI-NotI
• ACCN: NM_015373
• Insert Size: 1140 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Components: The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
• Reconstitution Method: 1. Centrifuge at 5,000xg for 5min.; 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.; 3. Close the tube and incubate for 10 minutes at room temperature.; 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.; 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
• Note: Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required.
• Shipping: Ambient

Reference Data

• RefSeq: NM_015373.3, NP_056188.1
• RefSeq Size: 1147 bp
• RefSeq ORF: 381 bp
• Locus ID: 25776
• UniProt ID: Q9Y3M2
• Cytogenetics: 22q13.1
• Protein Families: Transcription Factors
• Summary: Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]; Transcript Variant: This variant (1) represents the predominant transcript and encodes isoform (a), which is shorter at the N-terminus compared to isoform b.